Results 51 to 60 of about 4,880,316 (303)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Coordinated Development between Assistance to Tibet and Tourism Development: Spatial Patterns and Influencing Factors

open access: yesDiscrete Dynamics in Nature and Society, 2020
The Chinese government has provided various forms of assistance to the Tibet Autonomous Region and has substantially improved their facilities, which has had a positive influence on the development of tourism in Tibet.
Song Liu   +4 more
doaj   +1 more source

Types of coupling coordination degree between scientific and technological innovation and ecological environment optimization.

open access: yes, 2023
Types of coupling coordination degree between scientific and technological innovation and ecological environment optimization.
Yongzhen Wang (4631062)   +1 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Where is the pathway to sustainable urban development? Coupling coordination evaluation and configuration analysis between low-carbon development and eco-environment: A case study of the Yellow River Basin, China

open access: yesEcological Indicators, 2022
Coupling coordination is the core connotation of sustainable urban development. Few studies have considered the coupling coordination between low-carbon development and eco-environment (LC-EE) simultaneously for the key region, and ignored the ...
Lan Luo   +4 more
doaj   +1 more source

Coupling and coordination degree between foreign circulation and industrial green development.

open access: yes, 2023
Coupling and coordination degree between foreign circulation and industrial green development.
Jianlin He (4989536)
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Coupling Coordination Degree of Land, Ecology, and Food and Its Influencing Factors in Henan Province

open access: yesAgriculture
Studying the spatiotemporal evolution characteristics of the coupling coordination of the land–ecology–food system (LEF) aids in promoting green agricultural development and regional resource management.
Xian Yang   +6 more
doaj   +1 more source

Coupling coordination analysis of resources, economy, and ecology in the Yellow River Basin

open access: yesEcological Indicators, 2023
The development of the Yellow River Basin (YRB) has been constrained by resource utilization, ecological conservation, and economic growth. The aim of this study was to establish a theoretical framework for characterizing the relationships among ...
Guanhang Sui   +3 more
doaj   +1 more source

Research and analysis of coupling coordination degree between tourism industry and regional economy in Wuhu City [PDF]

open access: yes, 2021
Taking Wuhu City of Anhui Province as an example, this paper constructs two evaluation index systems of tourism industry and regional economic development respectively, and studies the coupling coordination situation and influencing factors of Wuhu City ...
Li Guanghong   +3 more
core   +1 more source

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