Results 61 to 70 of about 4,880,316 (303)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Analysis of the coupling degree between regional logistics efficiency and economic development coordination

PLOS ONE
This paper aims to study the relationship between regional logistics efficiency and economic development in 31 provinces of China and analyze their coupling coordination. To comprehensively evaluate the coordination between logistics and the economy, we introduced external indicators, such as carbon emissions, based on traditional evaluation indicators.
Na Li, Tianxing Ma, Xiaochun Deng
openaire   +3 more sources

Analysis on Coupling Coordination Degree between Intensive Urban Land Use and Urbanization in Hebei Province

Shuitu baochi yanjiu, 2013
Based on coupling coordination characteristics of intensive urban land use and urbanization,coupling coordination degree model and relative development degree evaluation model was built.Coupling coordination development degree and relative development ...
LI Yu-shuang1, GE Jing-feng1, LIANG Yan-qing1, LIU Ya-ai1   +3 more
doaj  

Research on the coupling measurement of medical education and health resource allocation under the background of healthy China

BMC Medical Education
Objective To analyze the coupling and coordination level of medical education and health resource allocation in China, and to provide scientific basis for promoting the high-quality development of medical education and the efficient allocation of health ...
Chen Jieting, Zhu Yan, Song Zhilong, Li Siyuan, Wu Xiangwei   +4 more
doaj   +1 more source

Head–torso–hand coordination in children with and without developmental coordination disorder [PDF]

, 2010
AIM: This study investigated the nature of coordination and control problems in children with developmental coordination disorder (DCD). METHOD: Seven adults (two males, five females, age range 20–28y; mean 23y, SD 2y 8mo) and eight children with DCD (
Sheehan, Sinead, Mon-Williams, M, Sheehan, S., Elders, V, Wilson, A.D., Wilson, Andrew D., Wilson, AD, Bhakta, B, Elders, V., Sheehan, S, Levesley, Martin, Mon-Williams, M., Levesley, M., Mon-Williams, Mark, Bhakta, B., Elders, Vera, Levesley, M, Bhakta, Bipin   +17 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Coupling and Coordination Development Between Urbanization and Eco-environment in Gansu Province

Shuitu baochi yanjiu, 2021
Taking 12 prefecture-level cities in Gansu Province as the research objects, based on entropy weight method and coupling coordination model, we analyzed the coordination degree's space-time dynamic evolution and influencing factors between urbanization ...
HAN Yan, Zhangyu Ting
doaj  

Absolute β convergence of the coupling coordination degree of the energy-economy-carbon emission system.

, 2022
Absolute β convergence of the coupling coordination degree of the energy-economy-carbon emission system.
Fengyuan Zhang (1424125), Zenglian Zhang (14216324), Zhiyuan Dong (10035265)   +2 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Research on misuses and modification of coupling coordination degree model in China [PDF]

JOURNAL OF NATURAL RESOURCES, 2021
Bin-ting DAI, Dan-dan ZHI, Liang REN, Wei KONG, Shu-jia WANG   +4 more
openaire   +1 more source