Results 71 to 80 of about 4,155,600 (295)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2021 Taking Wuhu City of Anhui Province as an example, this paper constructs two evaluation index systems of tourism industry and regional economic development respectively, and studies the coupling coordination situation and influencing factors of Wuhu City ...
Li Guanghong, Hu Yuan
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2023 Coupling degree types, coupling coordination degree types and their characteristics of the five industrial dimensions in 30 provinces and cities in China.
Kongtuan Lin (16648956) +2 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Frontiers in Environmental ScienceIntroductionMeasuring the coupling coordination degree between the innovation factor allocation system and the green economy development system, and deeply exploring the changing trends in the coupling coordination between innovation factors allocation ...
Kangshun Geng +3 more
doaj +1 more source
Research on the Coupling and Synergistic Development of Corporate ESG Performance and OFDI [PDF]
SHS Web of ConferencesThe demand for corporate green governance competence has significantly increased in the international market in recent years, with the disclosure of corporate ESG information emerging as a crucial public concern.
Huang Wenjing
doaj +1 more source
Correspondence between coupling coordination degree and coupling state.
Correspondence between coupling coordination degree and coupling state.
Changxin Liu (6520769) +4 more
core +1 more source