Results 91 to 100 of about 5,328,774 (332)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The Transport Performance of Feedback Coupled Brownian Ratchets
MATEC Web of Conferences, 2017 The directed transport properties of feedback coupled Brownian ratchets under the effect of external periodic force and load force are investigated. The influence of the coupling strength on the transport properties of coupled system is discussed in ...
Fan LiMing +3 more
doaj +1 more source
Sexual intimacy in couples is associated with longer telomere length [PDF]
Psychoneuroendocrinology, 2017 High-quality relationships have been shown to be beneficial for physical and mental health. This study examined overall relationship satisfaction and perceived stress as well as daily reports of partner support, partner conflict, and physical intimacy obtained over the course of one week in a sample of 129 high and low stress mothers.
Cabeza de Baca, Tomás +6 more
openaire +5 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The perfect waveguide coupler with universal impedance matching and transformation optics
NanophotonicsEfficient energy transfer is crucial in electromagnetic communication. Therefore, producing a waveguide coupler that achieves broadband, nonreflective transmission is a challenging task. With the advancement of silicon-based integrated photonic circuits,
Kim Myeongjin, Park Q-Han
doaj +1 more source
Universal Trimers induced by Spin-Orbit Coupling in Ultracold Fermi Gases
, 2013 In this letter we address the issue how synthetic spin-orbit (SO) coupling can strongly affect three-body physics in ultracold atomic gases. We consider a system which consists of three fermionic atoms, including two spinless heavy atoms and one spin-1/2
Cui, Xiaoling, Shi, Zhe-Yu, Zhai, Hui
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Inhomogeneous Mode-Coupling Theory and Growing Dynamic Length in Supercooled Liquids
, 2006 We extend Mode-Coupling Theory (MCT) to inhomogeneous situations, relevant for supercooled liquid in pores, close to a surface, or in an external field.
David R. Reichman +4 more
core +1 more source