Results 81 to 90 of about 294,366 (259)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The Influence of Torsion on Transmission Function Asymetric Twin Core Fibre

Advances in Electrical and Electronic Engineering, 2004
The transmission function of twin core fibre is determined by his fibre length and coupling length if only one of its cores is excited. For design of attenuation components or sensors it is useful known transmission dependence twin core fibres on ...
Daniel Kacik, Ivan Turek, Ivan Martincek
doaj  

Tilt-to-length coupling in LISA Pathfinder: Long-term stability

Physical Review D
The tilt-to-length coupling during the LISA Pathfinder mission has been numerically and analytically modeled for particular time spans. In this work, we investigate the long-term stability of the coupling coefficients of this noise. We show that they drifted slowly (by
Armano M., Audley H., Baird J., Binetruy P., Born M., Bortoluzzi D., Castelli E., Cavalleri A., Cesarini A., Cruise A. M., Danzmann K., De Deus Silva M., Diepholz I., Dixon G., Dolesi R., Ferraioli L., Ferroni V., Fitzsimons E. D., Freschi M., Gesa L., Giardini D., Gibert F., Giusteri R., Grimani C., Grzymisch J., Harrison I., Hartig M. S., Heinzel G., Hewitson M., Hollington D., Hoyland D., Hueller M., Inchauspé H., Jennrich O., Jetzer P., Johann U., Johlander B., Karnesis N., Kaune B., Killow C. J., Korsakova N., Lobo J. A., López-Zaragoza J. P., Maarschalkerweerd R., Mance D., Martín V., Martin-Polo L., Martin-Porqueras F., Martino J., McNamara P. W., Mendes J., Mendes L., Meshksar N., Nofrarias M., Paczkowski S., Perreur-Lloyd M., Petiteau A., Plagnol E., Ramos-Castro J., Reiche J., Rivas F., Robertson D. I., Russano G., Sanjuan J., Slutsky J., Sopuerta C. F., Sumner T., Texier D., Thorpe J. I., Vetrugno D., Vitale S., Wanner G., Ward H., Wass P. J., Weber W. J., Wissel L., Wittchen A., Zweifel P.   +77 more
openaire   +6 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

High power, broadband, coaxial to microstrip bi‐directional coupler in the VHF/UHF band

IET Science, Measurement & Technology
Broadband couplers consist usually of multiple coupled lines that are each a quarter wave‐length long. Herein, in contrast to conventional methods, a short length of a microstrip line is coupled to a coaxial line.
Tohid Naeimi, Arash Ahmadi
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Hydrodynamical properties of back reacted thermal plasma with finite ’t Hooft coupling correction

European Physical Journal C: Particles and Fields
In this work, holographic approach has been used to analyse the hydrodynamical properties of $$\mathcal {N}=4$$ N = 4 Super Yang–Mills thermal plasma with finite ’t Hooft coupling correction and flavour quarks dual to the AdS Gauss–Bonnet gravity in the ...
Rishi Pokhrel, Karma P. Sherpa, Indra K. P. Chettri, Tanay K. Dey   +3 more
doaj   +1 more source