Results 61 to 70 of about 1,206,762 (335)

Length-dependent electromechanical coupling in single muscle fibers. [PDF]

The Journal of general physiology, 1976
In single muscle fibers from the giant barnacle, a small decrease in muscle length decreases both the calcium activation and the peak isometric tension produced by a constant current stimulus. The effect is most pronounced if the length change immediately precedes the stimulation.
A M, Gordon, E B, Ridgway
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Running coupling constant and correlation length from Wilson loops

, 1994
We consider a definition of the QCD running coupling constant $\alpha(\mu)$ related to Wilson loops of size $r{\times}t$ with arbitrary fixed $t/r$. The schemes defined by these couplings are very close to the $\overline{\rm MS}$ scheme (i.e.\ the one ...
Aoyama, Bali, Billoire, Booth, Caracciolo, de Divitiis, Dotsenko, El-Khadra, Ettore Vicari, Kirschner, Luscher, Massimo Campostrini, Michael, Paolo Rossi, Rossi, Sommer   +15 more
core   +3 more sources

Finite size effects in the dynamics of glass-forming liquids [PDF]

, 2012
We present a comprehensive theoretical study of finite size effects in the relaxation dynamics of glass-forming liquids. Our analysis is motivated by recent theoretical progress regarding the understanding of relevant correlation length scales in liquids
Cristina Toninelli, Daniele Coslovich, Giulio Biroli, K. Binder, Ludovic Berthier, M. Allen, M. E. J. Newman, W. Götze, W. Kob, Walter Kob   +9 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Crossover from Spin-Density-Wave to Neel-like Ground state

, 1994
The characterization and evolution of a Spin Density Wave into the Quantum Neel ground state is considered in the context of a weak coupling theory of the half-filled Hubbard model.
A. A. Ovchinnikov, A. I. Larkin, A. J. Millis, A. J. Millis, A. Sokol, A. V. Chubokov, A. V. Chubukov, A. V. Chubukov, A. V. Chubukov, B. D. Josephson, B. I. Halperin, B. I. Shraiman, B. Keimer, D. C. Mattis, E. Lieb, F. D. M. Haldane, F. Woynarovich, H. Frahm, H. Frahm, H. J. Schulz, H. Shiba, H. Shiba, H. Shiba, J. Bonc✓a, J. Ferrer, J. Igarashi, J. R. Schrieffer, Jaime Ferrer, M. Ogata, M. Randeria, M. Randeria, N. D. Mermin, P. Fulde, P. Nozieres, P. W. Anderson, R. E. Walstedt, S. Chakravarty, V. J. Emery   +37 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Unraveling the ultra-broadband beam splitter based on parallel coupled waveguides

JPhys Photonics
An ultra-broadband beam splitter is theoretically realized using a directional parallel-cascaded coupled-waveguide structure, which is designed and investigated with the effective medium method and finite-difference time-domain method. The 1 dB bandwidth
Sheng Hsiung Chang
doaj   +1 more source

Study of Baffle Boundary and System Parameters on Liquid-Solid Coupling Vibration of Rectangular Liquid-Storage Structure

Shock and Vibration, 2016
In order to study the vibration problem of liquid-solid coupling of rectangular liquid-storage structure with horizontal elastic baffle, ignoring the influence of surface gravity wave, two different velocity potential functions corresponding to the ...
Wei Jing, Xuansheng Cheng, Wei Shi, Jin Fan, Huan Feng   +4 more
doaj   +1 more source