Results 111 to 120 of about 5,328,774 (332)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Weak and Strong coupling regimes in plasmonic-QED

, 2013
We present a quantum theory for the interaction of a two level emitter with surface plasmon polaritons confined in single-mode waveguide resonators.
C. Cohen-Tannoudji, C. Tai, D. Zueco, F. J. García-Vidal, G. W. Hanson, H. Breuer, L. Knöll, L. Martín-Moreno, L. Novotny, S. Haroche, T. Hümmer, U. Weiss, W. P. Schleich, W. Vogel   +13 more
core   +1 more source

Propagation-length independent SRS threshold in chirally-coupled-core fibers

Optics Express, 2011
Both analytical study and numerical simulations show that the propagation-length independent Stimulated Raman Scattering (SRS) threshold can be achieved by Stokes wave suppression in optical fibers. We propose a specific design based on Chirally-Coupled-Core (CCC) fibers with spectrally-tailored wavelength-selective transmission to suppress the Stokes ...
Xiuquan, Ma, I-Ning, Hu, Almantas, Galvanauskas   +2 more
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Optical Coupling Structures of Fiber-Optic Mach-Zehnder Interferometers Using CO2 Laser Irradiation

International Journal of Antennas and Propagation, 2014
The Mach-Zehnder interferometer (MZI) can be used to test changes in the refractive index of sucrose solutions at different concentrations. However, the popularity of this measurement tool is limited by its substantial size and portability.
Chien-Hsing Chen, Chih-Yu Hsu, Pei-Hsing Huang, Jian-Neng Wang, Wei-Te Wu   +4 more
doaj   +1 more source

Precision muon lifetime and capture experiments at PSI

, 2004
The muLan experiment at the Paul Scherrer Institute will measure the lifetime of the positive muon with a precision of 1 ppm, giving a value for the Fermi coupling constant G_F at the level of 0.5 ppm. Meanwhile, by measuring the observed lifetime of the
Bernard, Chen, Commins, F.E. Gray, Fearing, Gorringe, van Ritbergen   +6 more
core   +1 more source

Tilt-to-length coupling in LISA Pathfinder: Long-term stability

Physical Review D
The tilt-to-length coupling during the LISA Pathfinder mission has been numerically and analytically modeled for particular time spans. In this work, we investigate the long-term stability of the coupling coefficients of this noise. We show that they drifted slowly (by 1  μm/rad and 6×10−6 in 100 days) and were strongly correlated to temperature ...
Armano M., Audley H., Baird J., Binetruy P., Born M., Bortoluzzi D., Castelli E., Cavalleri A., Cesarini A., Cruise A. M., Danzmann K., De Deus Silva M., Diepholz I., Dixon G., Dolesi R., Ferraioli L., Ferroni V., Fitzsimons E. D., Freschi M., Gesa L., Giardini D., Gibert F., Giusteri R., Grimani C., Grzymisch J., Harrison I., Hartig M. S., Heinzel G., Hewitson M., Hollington D., Hoyland D., Hueller M., Inchauspé H., Jennrich O., Jetzer P., Johann U., Johlander B., Karnesis N., Kaune B., Killow C. J., Korsakova N., Lobo J. A., López-Zaragoza J. P., Maarschalkerweerd R., Mance D., Martín V., Martin-Polo L., Martin-Porqueras F., Martino J., McNamara P. W., Mendes J., Mendes L., Meshksar N., Nofrarias M., Paczkowski S., Perreur-Lloyd M., Petiteau A., Plagnol E., Ramos-Castro J., Reiche J., Rivas F., Robertson D. I., Russano G., Sanjuan J., Slutsky J., Sopuerta C. F., Sumner T., Texier D., Thorpe J. I., Vetrugno D., Vitale S., Wanner G., Ward H., Wass P. J., Weber W. J., Wissel L., Wittchen A., Zweifel P.   +77 more
openaire   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Nonminimally coupled dark matter in clusters of galaxies: a fully comprehensive analysis

European Physical Journal C: Particles and Fields
In this study, we explore how a non-minimal coupling between dark matter and gravity can affect the behavior of dark matter in galaxy clusters. We have considered the case of a disformal coupling, which leads to a modification of the Poisson equation ...
Saboura Zamani, Vincenzo Salzano, Dario Bettoni   +2 more
doaj   +1 more source

Low temperature saturation of phase coherence length in topological insulators

, 2019
Implementing topological insulators as elementary units in quantum technologies requires a comprehensive understanding of the dephasing mechanisms governing the surface carriers in these materials, which impose a practical limit to the applicability of ...
Banerjee, Mitali, Bhattacharyya, Semonti, Elizabeth, Suja, Ghosh, Arindam, Islam, Saurav, Kandala, Abhinav, Nhalil, Hariharan, Richardella, Anthony, Samarth, Nitin, Sen, Diptiman   +9 more
core   +1 more source