Results 91 to 100 of about 7,458,947 (249)
IEEE Photonics JournalThis study presents a novel asymmetrically coupled cavity (ACC) semiconductor laser structure designed to achieve stable single-mode operation in wider ridge waveguides, enhancing output power.
Tianqi Zhang +11 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Using Hermite Expansions for Fast and Arbitrarily Accurate Computation of the Expected Loss of a Loan Portfolio Tranche in the Gaussian Factor Model [PDF]
We propose a fast algorithm for computing the expected tranche loss in the Gaussian factor model with arbitrary accuracy using Hermite expansions. No assumptions about homogeneity of the portfolio are made.
Pavel Okunev
core
AgricultureTo solve the problem of the high loss rate of threshing devices during the mechanical harvesting of ratoon rice, we propose a method using the principle of rigid–flexible coupling in this paper to reduce losses.
Weijian Liu, Xuegeng Chen, Shan Zeng
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
, 2007 The dependence of the Q-factor of the microfiber coil resonator on different input/output couplings is investigated and compared. A method of slowly varying input/output coupling is presented to considerably simplify the fabrication of high-Q ...
Horak, P., Xu, F., Brambilla, G.
core +1 more source
A Transfer Function Method to Predict Transportation-Induced Building Vibration on Saturated Soil
BuildingsBuilding vibration induced by running trains or other loads is related to soil vibration, building coupling loss, and the building floor’s amplification factor.
Jinbao Yao, Nianping Wu, Yueyue Chen
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Jixie chuandong, 2013 Considering the gearbox with an external fluid coupling,the statistical energy model is introduced based on the basic principles of statistical energy analysis.The time-varying mesh stiffness and errors are also taken into accout in calculation of ...
赵蓓蕾 +3 more
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source