Results 51 to 60 of about 6,557,444 (383)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Molecules, 2020 To explore plausible reaction pathways of the cross-coupling reaction between a haloalkane and an aryl metal reagent catalyzed by an iron–phosphine complex, we examine the reaction of FeBrPh(SciOPP) 1 and bromocycloheptane employing density functional ...
Akhilesh K. Sharma, Masaharu Nakamura
doaj +1 more source
DNA-Mediated Electron Transfer in Naphthalene-Modified Oligonucleotides [PDF]
, 2010 Naphthalene-modified oligonucleotides have been synthesized and characterized with respect to electron transfer chemistry. Using the Sonogashira coupling reaction, naphthalene can be covalently anchored onto a modified uridine through an ethynyl linkage.
Barton, Jacqueline K. +2 more
core +3 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Molecules, 2014 New 1,2,4-triazole colorants were obtained, in high yields, by coupling 3-ethylthio-5-cyanomethyl-4-phenyl-1,2,4-triazole (1) with diazotized aniline derivatives 2, 4 and 6. The azo dyes prepared in this work may exist in three tautomeric forms.
Mariam Al-Sheikh +3 more
doaj +1 more source
Molecules, 2022 Hiyama cross-coupling is a versatile reaction in synthetic organic chemistry for the construction of carbon–carbon bonds. It involves the coupling of organosilicons with organic halides using transition metal catalysts in good yields and high ...
Rida Noor +7 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Nano Biomedicine and Engineering, 2018 New azo ligand, 2[(Aminoantipyren) azo]-4, 5-bis(4-Methoxyphenyl)-H imidazole, (AAMPI) was prepared through coupling reaction of 4-amino antipyrine with 4, 5-bis (4-methoxyphenyl) imidazole.
Siham Sami Al-Muhanaa +1 more
doaj +1 more source
Current Research in Green and Sustainable Chemistry, 2022 Biogenic palladium nanostructures (NS) are synthesized by utilising pomegranate peels which are generally considered as agro-wastes. A simple methodology without the use of external reducing agent has been applied to achieve uniform flowerlike ...
Sameeran Kumar Das +7 more
doaj +1 more source
, 2008 We examine theoretically production of the neutron-rich $^{10}_{\Lambda}$Li hypernucleus by a double-charge exchange ($\pi^-$, $K^+$) reaction on a $^{10}$B target with distorted-wave impulse approximation calculations.
A. Bohr +5 more
core +1 more source