Results 111 to 120 of about 4,509,075 (305)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Short of Transformation: American ADN Students\u27 Thoughts, Feelings, and Experiences of Studying Abroad in a Low-Income Country [PDF]

open access: yes, 2012
ADN students are a large yet distinct subgroup of nursing students who require research and understanding. The purpose of this study was to describe the thoughts, feelings, and experiences of American associate degree nursing (ADN) students who ...
Belknap, Ruth, Foronda, Cynthia
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Single query learning from abelian and non-abelian Hamming distance oracles [PDF]

open access: yes, 2009
We study the problem of identifying an n-bit string using a single quantum query to an oracle that computes the Hamming distance between the query and hidden strings. The standard action of the oracle on a response register of dimension r is by powers of
Meyer, David A., Pommersheim, James
core   +1 more source

The New York-New Jersey Boundary Controversy: John Marshall and the Nullification Crisis

open access: yes, 1992
In 1832 a long-standing boundary dispute between New York and New Jersey complicated the work of Chief Justice John Marshall and President Andrew Jackson.
Birkner, Michael J.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Exploration of the solar system [PDF]

open access: yes
A sourcebook of information on the solar system and the technology used for its exploration is presented. An outline of the potential achievements of solar system exploration is given along with a course of action which maximizes the rewards to ...
Grey, J., Henderson, A., Jr.
core   +1 more source

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