Results 61 to 70 of about 877,837 (312)
Chronic diseases in Australia: blueprint for preventive action [PDF]
This paper identifies strategic priorities for taking action to prevent chronic diseases. It is the second report by the Mitchell Institute on this issue.
Sharon Willcox, Willcox, Sharon
core
SMACH (Multi-Agent Human Activity Simulation) is a social simulation platform that is part of EDF’s Research and Development framework aimed at developing simulation to anticipate and reduce energy consumption in homes. In this paper, we develop the idea
Yvon Haradji +7 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Technological innovations contribute to developments in the technical culture of sports. The current field of competitive sailing provides an opportunity to study the development of a technical culture linked to the spread of an innovation in equipment –
Éric Terrien +2 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Sketching for military courses of action diagrams [PDF]
A serious barrier to the digitalization of the US military is that commanders find traditional mouse/menu, CAD-style interfaces unnatural. Military commanders develop and communicate battle plans by sketching courses of action (COAs). This paper describes nuSketch Battlespace, the latest version in an evolving line of sketching interfaces that ...
Kenneth D. Forbus +2 more
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
This was to be a talk given before the Portland State University, Impact Summit Pitch Fest in Portland, Oregon in early February 2018. Unfortunately, it was not picked. I fear the reason may be the subject matter: a future living with early warning systems, hardening human settlements, and giving survival options to people who want to stay in place as ...
openaire +2 more sources
This case describes the ethical and legal challenges facing Dr. Caroline Webster, Director of Graduate Business Programs at MNU. She was facing one of the more unpleasant tasks of her job in determining how to proceed with a complaint by one of the university’s master’s students by the name of Bob Golden.
Louis Peter D'Elia +2 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

