Results 71 to 80 of about 4,509,075 (305)

Équipements sportifs innovants et développement d’une culture technique. L’exemple de la navigation sur des voiliers « volants »

open access: yesActivités, 2020
Technological innovations contribute to developments in the technical culture of sports. The current field of competitive sailing provides an opportunity to study the development of a technical culture linked to the spread of an innovation in equipment –
Éric Terrien   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Can virtuous people emerge from tragic dilemmas having acted well? [PDF]

open access: yes, 2007
A tragic dilemma is thought to arise when an agent, through no fault of her own, finds herself in a situation where she must choose between two courses of action, both of which it would be wrong to undertake.
van Zyl, Liezl
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Racial / Ethnic and Gender Diversity in the Orchestra Field [PDF]

open access: yes, 2016
For all cultural institutions, knowledge and information are becoming critical tools in the work of navigating a course through this new landscape. In particular, there is a recognized value in learning from the past in order to inform action for the ...
James Doeser
core  

L’activité d’enseignants experts en Education Physique et Sportive : une étude de cas sur les formes, les fonctions et la pertinence des communications non verbales en situation

open access: yeseJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2016
The objective of this paper is to analyze the activity of expert PE teachers in situation, with a focal on the forms, functions and relevance of their non-verbal communication (NVC) situation.
Jérôme Visioli, Oriane Petiot, Luc Ria
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Pain management for chronic musculoskeletal conditions : the development of an evidence-based and theory-informed pain self-management course [PDF]

open access: yes, 2013
Objective: To devise and test a self-management course for chronic pain patients based on evidence and underpinned by theory using the Medical Research Council (MRC) framework for developing complex interventions.
Carnes, Dawn   +5 more
core   +3 more sources

Former au métier d’éducateur socio-sportif : exemple d’un dispositif collaboratif centré sur l’expérience d’intervention

open access: yeseJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2016
This research takes place at University of Orleans in the area of physical education and sport teaching. More precisely, this research investigates the training of social sports educators.The study is conducted within the theoretical framework of the ...
Karine Paret, Nathalie Gal-Petitfaux
doaj   +1 more source

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