Results 41 to 50 of about 3,934,989 (303)
Frontiers in NutritionProteins and polyphenols are abundant in the daily diet of humans and their interactions influence, among other things, the texture, flavor, and bioaccessibility of food.
Kangyi Zhang +10 more
doaj +1 more source
Covalent and non‐covalent interaction of chymotrypsin with α2‐macroglobulin
FEBS Letters, 1987 The pattern of covalent crosslinking between human α2‐macroglobulin (α2M) and chymotrypsin has been investigated by chromatography and polyacrylamide gel electrophoresis in denaturing medium. Reaction with a single mol of chymotrypsin per mol α2M results in the formation of a 95% covalent 1:1 chymotrypsin‐α2M complex and in the proteolytic cleavage of ...
Pochon, François +3 more
openaire +2 more sources
Small Molecules, Non-Covalent Interactions, and Confinement [PDF]
Molecules, 2020 This review gives an overview of current trends in the investigation of small guest molecules, confined in neat and functionalized mesoporous silica materials by a combination of solid-state NMR and relaxometry with other physico-chemical techniques.
Gerd Buntkowsky, Michael Vogel
openaire +4 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Non-covalent binding interaction between phthalic acid esters and DNA
Environment International, 2022 The interaction of phthalic acid esters (PAEs) with DNA is known to be responsible for the disruption of endocrine functions and the teratogenic and carcinogenic effects.
Hao Cheng +6 more
doaj +1 more source
Covalent and Non-Covalent Binding Free Energy Calculations for Peptidomimetic Inhibitors of SARS-CoV-2 Main Protease [PDF]
, 2020 COVID-19, the disease caused by the newly discovered coronavirus — SARS-CoV-2, has created global health, social, and economic crisis. At the time of writing (November 12, 2020), there are over 50 million confirmed cases and more than 1 million reported ...
Abd Al-Aziz A., Abu-Saleh +1 more
core +1 more source
Covalent Bonding Aptamer with Enhanced SARS-CoV-2 RBD-ACE2 Blocking and Pseudovirus Neutralization Activities [PDF]
, 2021 SARS-CoV-2 uses its spike protein receptor-binding domain (RBD) to interact with the angiotensin-converting enzyme 2 (ACE2) receptor on host cells. Inhibitors of the RBD-ACE2 interaction are therefore promising drug candidates in treating COVID-19. Here,
Yu, Xiang, Zichen, Qin, Yiying, Zhu
core +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2020 BRD4, a member of the bromodomain and extraterminal domain (BET) family, has emerged as a promising epigenetic target in cancer and inflammatory disorders.
Michael D. Olp (4494292) +9 more
core +2 more sources
Shipin gongye ke-jiTo investigate the effect of the interaction between protocatechuic acid (PCA) and gelatin on the functional properties and stability of gelatin-PCA complexes. Gelatin-PCA complexes were prepared by non-covalent and covalent binding.
Ran LIU +5 more
doaj +1 more source