Results 51 to 60 of about 392,552 (294)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effects of Non-covalent/Covalent Interactions on Functional Properties and Stability of Gelatin-PCA Complexes

Shipin gongye ke-ji
To investigate the effect of the interaction between protocatechuic acid (PCA) and gelatin on the functional properties and stability of gelatin-PCA complexes. Gelatin-PCA complexes were prepared by non-covalent and covalent binding.
Ran LIU, Qinghua ZENG, Shuang CHENG, Jingyu LI, Xiaohong PAN, Lei WANG   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

non-covalent interactions

Citation: 'non-covalent interactions' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09875 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
Marcus Elstner, Qiang Cui, Maja Gruden
openaire   +2 more sources

Dynamic covalent epoxy network of hyperbranched-synergistic-supramolecular: Catalyst-free reprocessing, and application in carbon fiber composites recycling

Supramolecular Materials
Plastic recycling, especially the recycling of thermosets, is a crucial step towards improving waste management and achieving economic recycling. Here, a method utilizing non-covalent supramolecular interactions and synergistic hyperbranched structures ...
Yueran He, Yanlin Liu, Zhen Yu, Xiangyu Zhou, Jin Zhu, Zhaobin Tang   +5 more
doaj   +1 more source

Signature of a chemical bond in the conductance between two metal surfaces [PDF]

, 2003
Conductance in monatomic metal contacts is quantized; it increases in discrete steps of one conductance quantum 2e(2)/h. By contrast, in a vacuum barrier between two metal surfaces we find that conductance increases linearly and continuously with the ...
Fisher, AJ, Hofer, WA
core  

Non-Covalent Interactions Mimic the Covalent: An Electrode-Orthogonal Self-Assembled Layer

Journal of the American Chemical Society, 2023
Charge-transfer events central to energy conversion and storage and molecular sensing occur at electrified interfaces. Synthetic control over the interface is traditionally accessed through electrode-specific covalent tethering of molecules. Covalent linkages inherently limit the scope and the potential stability window of molecularly tunable ...
Deepak Badgurjar, Madison Huynh, Benjamin Masters, Anna Wuttig   +3 more
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Effect of Volvariella volvacea Extract on the Intermolecular Force of Beef Myofibrillar Protein during Flavor Adsorption

Shipin gongye ke-ji, 2022
In order to explore the effect of edible mushroom on the protein flavor adsorption capacity of meat products, beef myofibrillar protein (MP) was treated with Volvariella volvacea extract (VV) and the changes of MP protein intermolecular force and flavor ...
Zhenglong QING, Xueming LIU, Daobang TANG, Yaosheng LIN, Xuping WANG, Huaigu YANG, Jinhao ZOU, Jingrong CHENG   +7 more
doaj   +1 more source

Stretching and relaxation dynamics in double stranded DNA [PDF]

, 2003
We study numerically the mechanical stability and elasticity properties of duplex DNA molecules within the frame of a network model incorporating microscopic degrees of freedom related with the arrangement of the base pairs.
Austin, Barbi, Bockelmann, Bockelmann, Bockelmann, Bouchiat, Bouchiat, Bouchiat, Bustamante, Clausen-Schaumann, Cluzel, Cocco, Cocco, Cocco, Coleman, Crisona, D. Hennig, Essevaz-Roulet, Gorin, J.F.R. Archilla, Léger, Marko, Marko, Marko, Moroz, Nelson, Olson, Olson, Peyrard, Smith, Smith, Strick, Stryer, Thomen, Wang   +34 more
core   +2 more sources