Results 61 to 70 of about 390,156 (271)
Food Chemistry: XImproving anthocyanin stability is a major challenge for the food industry. Studies have revealed that the interaction with pectin through non-covalent bonds can improve the anthocyanin stability, thus showing the potential to alleviate the above ...
Chenyang Shi +7 more
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Deciphering the nature of ion-graphene interaction
Physical Review Research, 2020 Ion-specific interactions with materials are important for the design of ion-based energy and information devices, which are studied here with a focus on alkali-earth-metal and transition-metal ions in the context of carbon nanofluidics.
Ke Zhou, Zhiping Xu
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COVALENCY EFFECTS IN HYPERFINE INTERACTIONS
Le Journal de Physique Colloques, 1974 The effects of covalency and overlap distortion on the spin and charge densities in mainly ionic materials are discussed and related to the hyperfine interactions. A linear combination of atomic orbitals is used although expansions and contractions of the wave functions relative to the free ion wave functions are also considered.
Sawatzky, G., van Der Woude, F.
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The surface site interaction point approach to non-covalent interactions
Chemical Society Reviews, 2022 Non-covalent interactions are described using the SSIPs. Simple rules of thumb for predicting binding constants for any functional group interaction in any solvent are described, as well as general treatments of molecular properties like partition.
Storer, Maria Chiara +1 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
MoleculesThe SARS-CoV-2 main protease (Mpro), essential for viral replication, remains a prime target for antiviral drug design against COVID-19 and related coronaviruses.
Adedapo Olosunde, Xiche Hu
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Molecules, 2022 Haspin, an atypical serine/threonine protein kinase, is a potential target for cancer therapy. 5-iodotubercidin (5-iTU), an adenosine derivative, has been identified as a potent Haspin inhibitor in vitro.
Yujing Zhou, Ming Wah Wong
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A Process Calculus for Molecular Interaction Maps
, 2009 We present the MIM calculus, a modeling formalism with a strong biological basis, which provides biologically-meaningful operators for representing the interaction capabilities of molecular species.
Andrea Maggiolo-Schettini +33 more
core +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Peptide‐based covalent inhibitors of protein–protein interactions
Journal of Peptide Science, 2022 Protein–protein interactions (PPI) are involved in all cellular processes and many represent attractive therapeutic targets. However, the frequently rather flat and large interaction areas render the identification of small molecular PPI inhibitors very challenging. As an alternative, peptide interaction motifs derived from a PPI interface can serve as
Paulussen, Felix M., Grossmann, Tom N.
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