Results 41 to 50 of about 41,033 (277)
MasterChem: Cooking 2D-polymers [PDF]
2D-polymers are still dominated by graphene and closely related materials such as boron nitride, transition metal sulphides and oxides. However, the rational combination of molecules with suitable design is already showing the high potential of chemistry
Amo-Ochoa, P. +2 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Design of Covalent Organic Frameworks for Methane Storage [PDF]
We designed 14 new covalent organic frameworks (COFs), which are expected to adsorb large amounts of methane (CH_4) at 298 K and up to 300 bar. We have calculated their delivery uptake using grand canonical Monte Carlo (GCMC) simulations.
Goddard, William A., III +2 more
core +1 more source
Structure elucidation of polyheptazine imide by electron diffraction — a templated 2D carbon nitride networkw [PDF]
Structure elucidation of a condensed carbon IV) nitride with a stoichiometry close to C3N4 by electron diffraction reveals a two-dimensional planar heptazine-based network containing isolated melamine molecules in the trigonal ...
Döblinger, Markus +5 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Pore partition in two-dimensional covalent organic frameworks
Covalent organic frameworks (COFs) have emerged as a kind of crystalline polymeric materials with high compositional and geometric tunability. Most COFs are currently designed and synthesized as mesoporous (2–50 nm) and microporous (1–2 nm) materials ...
Xiaoyi Xu +5 more
doaj +1 more source
Straightforward preparation of fluorinated covalent triazine frameworks with significantly enhanced carbon dioxide and hydrogen adsorption capacities [PDF]
The development of advanced functional porous materials for efficient carbon capture and separation is of prime importance with respect to energy and environmental sustainability and employing covalent triazine frameworks as the adsorbents for carbon ...
De Geyter, Nathalie +5 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Covalent Organic Frameworks for Photocatalysis
AbstractThe global energy crisis and environmental concerns are driving research into renewable energy and sustainable energy conversion and storage technologies. Solar energy, as an ideal sustainable resource, has significant potential to contribute to the goal of net‐zero carbon emissions if effectively harnessed and converted into a reliable and ...
Bikash Mishra +6 more
openaire +2 more sources

