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Clinics and Research in Hepatology and Gastroenterology
Covalently closed circular DNA (cccDNA) is a stable, episomal form of HBV DNA. cccDNA is a true marker for the intrahepatic events in controlled CHB infection. Quantifying cccDNA is critical for monitoring disease progression and efficacy of anti-viral therapies.
Nirupama Trehanpati +8 more
openaire +2 more sources
Covalently closed circular DNA (cccDNA) is a stable, episomal form of HBV DNA. cccDNA is a true marker for the intrahepatic events in controlled CHB infection. Quantifying cccDNA is critical for monitoring disease progression and efficacy of anti-viral therapies.
Nirupama Trehanpati +8 more
openaire +2 more sources
The Southeast Asian journal of tropical medicine and public health, 2010
Covalently closed circular DNA (cccDNA) is a unique episomal replicative intermediate molecule of hepatitis B virus (HBV) which plays a key role in viral persistence. The aim of this study was to prove cccDNA persistence in the liver tissue of patients negative for hepatitis B surface antigen (HBsAg) and positive for antibody to hepatitis core antigen (
Roongruedee, Chaiteerakij +3 more
openaire +1 more source
Covalently closed circular DNA (cccDNA) is a unique episomal replicative intermediate molecule of hepatitis B virus (HBV) which plays a key role in viral persistence. The aim of this study was to prove cccDNA persistence in the liver tissue of patients negative for hepatitis B surface antigen (HBsAg) and positive for antibody to hepatitis core antigen (
Roongruedee, Chaiteerakij +3 more
openaire +1 more source
A Novel Mouse Model Harboring Hepatitis B Virus Covalently Closed Circular DNA
Cellular and Molecular Gastroenterology and Hepatology, 2022Yuchen Xia, Kaitao Zhao, Chengliang Zhu
exaly