Using Propensity Score Weighting With Clustered Data When the Treatment Is Applied at the Level of the Cluster and Outcomes Are Assessed at the Level of the Individual: The Observational Analog of Cluster Randomization Trials. [PDF]
Austin PC.
europepmc +1 more source
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles +14 more
wiley +1 more source
Score Matching for Differential Abundance Testing of Compositional High-Throughput Sequencing Data. [PDF]
Ostner J, Li H, Müller CL.
europepmc +1 more source
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier +12 more
wiley +1 more source
A review and evaluation of doubly robust approaches for estimating average treatment effects. [PDF]
Zhang J, Lüdtke O, Robitzsch A.
europepmc +1 more source
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro +2 more
wiley +1 more source
PKGPT: Expert-Orchestrated Recursive LLM Agent for Automated NONMEM PopPK Modeling with Human Benchmarking. [PDF]
Kwack H +5 more
europepmc +1 more source
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian +4 more
wiley +1 more source
Neurodevelopment and psychosocial adjustment in children with early surgical ventricular septal defect repair: exploring the influence of surgery-related variables across childhood and adolescence. [PDF]
Gerlach J +5 more
europepmc +1 more source
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source

