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Metaheuristics for pharmacometrics [PDF]
CPT: Pharmacometrics & Systems Pharmacology, 2021 Metaheuristics is a powerful optimization tool that is increasingly used across disciplines to tackle general purpose optimization problems. Nature‐inspired metaheuristic algorithms is a subclass of metaheuristic algorithms and have been shown to be ...
Seongho Kim +4 more
doaj +5 more sources
Pharmaceutics, 2022 Pharmacometrics is a multidisciplinary field utilizing mathematical models of physiology, pharmacology, and disease to describe and quantify the interactions between medication and patient.
Frank Bennis +2 more
exaly +3 more sources
Pharmacometrics in tuberculosis: progress and opportunities [PDF]
International Journal of Antimicrobial Agents, 2022 Tuberculosis (TB) remains one of the leading causes of death by a communicable agent, infecting up to one-quarter of the world's population, predominantly in disadvantaged communities. Pharmacometrics employ quantitative mathematical models to describe the relationships between pharmacokinetics and pharmacodynamics, and to predict drug doses, exposures
Elin Svensson +2 more
exaly +4 more sources
AI for NONMEM Coding in Pharmacometrics Research and Education: Shortcut or Pitfall? [PDF]
CPT: Pharmacometrics & Systems PharmacologyArtificial intelligence (AI) is increasingly being explored as a tool to support pharmacometric modeling, particularly in addressing the coding challenges associated with NONMEM.
Wenhao Zheng +5 more
doaj +2 more sources
Pharmacometrics in the Age of Large Language Models: A Vision of the Future
PharmaceuticsBackground: Large Language Models (LLMs) have driven significant advances in artificial intelligence (AI), with transformative applications across numerous scientific fields, including biomedical research and drug development.
Paolo Magni +2 more
exaly +3 more sources
Advancing Pharmacometrics in Africa: Insights and Perspectives From the 2025 Pharmacometrics Africa Conference. [PDF]
Clin Pharmacol TherPharmacometrics (PMX) in Africa has transitioned from foundational capacity‐building to job creation, scientific leadership, regulatory influence, and health innovation. To accelerate this progress, the 2025 Pharmacometrics Africa Conference (PMXAC‐2025) convened key stakeholders to consolidate the continental PMX community, review progress in local ...
Adeagbo BA +12 more
europepmc +3 more sources
The Role of Pharmacometrics in Advancing the Therapies for Autoimmune Diseases
PharmaceuticsAutoimmune diseases (AIDs) are a group of disorders in which the immune system attacks the body’s own tissues, leading to chronic inflammation and organ damage.
Artur Świerczek +2 more
exaly +3 more sources
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
CPT: Pharmacometrics & Systems PharmacologyTrained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries.
Goonaseelan (Colin) Pillai +10 more
doaj +2 more sources
Concept and utility of population pharmacokinetic and pharmacokinetic/pharmacodynamic models in drug development and clinical practice [PDF]
Arhiv za farmaciju, 2021 Due to frequent clinical trial failures and consequently fewer new drug approvals, the need for improvement in drug development has, to a certain extent, been met using model-based drug development.
Roganović Maša +6 more
doaj +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2021 Pharmacometrics is an emerging science that interprets drug, disease, and trial information in a mathematical fashion to inform and facilitate efficient drug development and/or regulatory decisions.
Ming Zhao +9 more
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