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Metaheuristics for pharmacometrics [PDF]
CPT: Pharmacometrics & Systems Pharmacology, 2021 Metaheuristics is a powerful optimization tool that is increasingly used across disciplines to tackle general purpose optimization problems. Nature‐inspired metaheuristic algorithms is a subclass of metaheuristic algorithms and have been shown to be ...
Seongho Kim +4 more
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Pharmaceutics, 2022 Pharmacometrics is a multidisciplinary field utilizing mathematical models of physiology, pharmacology, and disease to describe and quantify the interactions between medication and patient.
Alexander Janssen, Frank C Bennis
exaly +3 more sources
AI for NONMEM Coding in Pharmacometrics Research and Education: Shortcut or Pitfall? [PDF]
CPT: Pharmacometrics & Systems PharmacologyArtificial intelligence (AI) is increasingly being explored as a tool to support pharmacometric modeling, particularly in addressing the coding challenges associated with NONMEM.
Wenhao Zheng +5 more
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The Role of Pharmacometrics in Advancing the Therapies for Autoimmune Diseases
PharmaceuticsAutoimmune diseases (AIDs) are a group of disorders in which the immune system attacks the body’s own tissues, leading to chronic inflammation and organ damage.
Artur Świerczek +2 more
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Concept and utility of population pharmacokinetic and pharmacokinetic/pharmacodynamic models in drug development and clinical practice [PDF]
Arhiv za farmaciju, 2021 Due to frequent clinical trial failures and consequently fewer new drug approvals, the need for improvement in drug development has, to a certain extent, been met using model-based drug development.
Roganović Maša +6 more
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CPT: Pharmacometrics & Systems Pharmacology, 2021 Pharmacometrics is an emerging science that interprets drug, disease, and trial information in a mathematical fashion to inform and facilitate efficient drug development and/or regulatory decisions.
Ming Zhao +9 more
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Advances in Pharmacological and Pharmaceutical Sciences, 2023 Pharmacotherapy, in many cases, is practiced at a suboptimal level of performance in low- and middle-income countries (LMICs) although stupendous amounts of data are available regularly.
Muhammad Usman +5 more
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Pharmacometrics approaches and its applications in diabetes: An overview
Journal of Pharmacy and Bioallied Sciences, 2021 Type 2 diabetes mellitus is the most prevalent and progressive in nature. As the time progress, the multifaceted complications and comorbidities associated to diabetes worsen in the form of macrovascular or microvascular or both. Pharmacometrics modeling
Sohail Aziz +3 more
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Variable or variate? A conundrum in pharmacometrics exposure–response models
CPT: Pharmacometrics & Systems Pharmacology, 2023 Key elements of scientific writing—consistency and clarity—can be compromised in case of inaccurate use of methodological terms, especially in complex and multidisciplinary scientific fields.
Ana‐Marija Grisic +3 more
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CPT: Pharmacometrics & Systems Pharmacology, 2021 Pediatric extrapolation is essential for bringing treatments to the pediatric population, especially for indications where the recruitment of pediatric patients into clinical trials is difficult and where fully powered trials are impossible.
Thomas Dumortier +2 more
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