Results 201 to 210 of about 595,073 (274)

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis from ELSA‐Brasil

Arthritis Care &Research, Accepted Article.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within ELSA‐Brasil included 585 participants (86 RA, 499 controls). Longitudinal analyses were restricted to those
Patrícia Fonseca Estrada, Marcos R. N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo Andrade Lotufo, Alessandra C.Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Can We Trust PAICs in Rare Diseases? Methodological Challenges and Limitations. [PDF]

J Mark Access Health Policy
Parkitny M, Aballéa S, Wojciechowski P, Toumi M.   +3 more
europepmc   +1 more source

Race and Household Income are Associated with Disease Outcomes in Pediatric Patients with ANCA‐associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, Accepted Article.
Objectives Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric anti‐neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race/ethnicity and household income are associated with severe AAV disease and renal outcomes among ...
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

The Regularized Horseshoe for Covariate Selection Improves Convenience and Predictive Performance in Population PK/PD Models. [PDF]

CPT Pharmacometrics Syst Pharmacol
Pourzanjani A, Davis C.
europepmc   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Methodological Challenges of Emulating a Target Trial to Assess Effectiveness of Timing of PCSK9 Inhibitor Treatment Initiation Post Myocardial Infarction. [PDF]

Pharmacoepidemiol Drug Saf
Cars T, Gustafsson S, Chan Q, Dhalwani N, Kent ST, Briggs A, Gale CP, Gitt A, Jukema JW, Steg PG, Sundström J, James S, Hagström E, Brookhart MA.   +13 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Incorporating Data Sets With Multiple Sources of Uncertainty in Integrated Species Distribution Models. [PDF]

Ecol Evol
Lunt F, Scher CL, Mummah RO, Miller DAW.
europepmc   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, EarlyView.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source