Results 231 to 240 of about 595,073 (274)

Exposure-Response Analyses of Datopotamab Deruxtecan (Dato-DXd) in Patients with Hormone Receptor (HR) Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer. [PDF]

J Clin Pharmacol
Tang Z, Lim K, Jiang Y, Denduluri N, Rokutanda N, Pan Y, Hong Y, Ren S, Vajjah P, Zhou D.   +9 more
europepmc   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Score-Based Tests With Fixed Effects Person Parameters in Item Response Theory: Detecting Model Misspecification Including Differential Item Functioning. [PDF]

Appl Psychol Meas
Debelak R, Driver CC.
europepmc   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Causal Covariate Selection for the Regression Calibration Method for Exposure Measurement Error Bias Correction. [PDF]

Stat Med
Tang W, Spiegelman D, Wu Y, Wang M.
europepmc   +1 more source

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

Advanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He, Jing Li, Tian Guan, Yifei Ma, Zimo Zhao, Yanxia Wang, Hongjing Chen, Yingming Xu, Shuang Ge, Yexing Zhang, Yizhi Wang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Qingxia Hou, Shuyan Zhao, Xiaoqin Wang, Lili Ma, Peizhen Hu, Qiang Huang, Zihan Wang, Zhiyuan Shen, Junru Cheng, Siqi Zeng, Jiurun Chen, Zhen Song, Chao He, Zhe Wang, Yonghong He   +28 more
wiley   +1 more source

Flexible yet Sparse Bayesian Survival Models With Time-Varying Coefficients and Unobserved Heterogeneity. [PDF]

Stat Med
Knaus P, Winkler D, Schoppmann SF, Jomrich G.   +3 more
europepmc   +1 more source

Causal Directed Acyclic Graphs to Mitigate Confounding Bias in Exposure-Response Analyses. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goulooze SC, Vong C, Hu C, Dumortier T, Mercier F.   +4 more
europepmc   +1 more source

Population Pharmacokinetic Modeling of Intravenous Topiramate in Patients with Epilepsy or Migraine. [PDF]

J Clin Pharmacol
Bamgboye AO, Coles LD, Suriyapakorn B, Mishra U, Kriel RL, Leppik IE, White JR, Cloyd JC.   +7 more
europepmc   +1 more source

Association between usual protein intake and muscle function in older U.S. adults: a target-trial emulation using NHANES 2011-2018. [PDF]

J Int Soc Sports Nutr
Ling Y, Hou MX, Riaz M, Rahman NU.
europepmc   +1 more source