Results 91 to 100 of about 2,231,738 (318)

Covariate-constrained randomization for cluster randomized trials in the long-term care setting: Application to the TRAIN-AD trial

open access: yesContemporary Clinical Trials Communications, 2020
Little has been reported on strategies to ensure key covariate balance in cluster randomized trials in the nursing home setting. Facilities vary widely on key characteristics, small numbers may be randomized, and staggered enrollment is often necessary ...
Michele L. Shaffer   +3 more
doaj   +1 more source

Covariate balance for the good vision and poor vision groups before and after MDM.

open access: yes, 2022
Covariate balance for the good vision and poor vision groups before and after MDM.
Frederik Sagemüller (8580681)   +2 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

IJMPR Didactic Paper: Weighting for Causal Inference in Mental Health Research

open access: yesInternational Journal of Methods in Psychiatric Research
Objective Inverse probability weighting is a fundamental and general methodology for estimating the causal effects of exposures and interventions, but standard approaches to constructing such weights are often suboptimal.
Eric R. Cohn, José R. Zubizarreta
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

The effect of dichotomization of skewed adjustment covariates in the analysis of clinical trials

open access: yesBMC Medical Research Methodology, 2023
Baseline imbalance in covariates associated with the primary outcome in clinical trials leads to bias in the reporting of results. Standard practice is to mitigate that bias by stratifying by those covariates in the randomization.
Alan Herschtal
doaj   +1 more source

Pre- and post-covariate balance among CTO and open cohorts after entropy balancing.

open access: yes, 2023
Pre- and post-covariate balance among CTO and open cohorts after entropy balancing.
Aimal Khan (4372159)   +8 more
core   +1 more source

Assessing the Impact of Propensity Score Estimation and Implementation on Covariate Balance and Confounding Control Within and Across Important Subgroups in Comparative Effectiveness Research

open access: yesMedical Care, 2014
Purpose:Researchers are often interested in estimating treatment effects in subgroups controlling for confounding based on a propensity score (PS) estimated in the overall study population.
C. Girman   +5 more
semanticscholar   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

How large are the consequences of covariate imbalance in cluster randomized trials: a simulation study with a continuous outcome and a binary covariate at the cluster level

open access: yesBMC Medical Research Methodology, 2016
Background The number of clusters in a cluster randomized trial is often low. It is therefore likely random assignment of clusters to treatment conditions results in covariate imbalance.
Mirjam Moerbeek, Sander van Schie
doaj   +1 more source

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