Results 71 to 80 of about 604,899 (363)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Cover Crop Termination & Reduced Tillage Study [PDF]

, 2010
In 2010, the University of Vermont Extension conducted the second year of an experiment to evaluate the impact of cover crop termination and reduced tillage strategies on soil health, soil nitrogen dynamics, and corn silage yield and quality. The goal is
Cummings, Erica, Darby, Heather, Gervais, Amanda, Halteman, Philip, Madden, Rosalie   +4 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Effect of management spontaneous cover crop on rosy apple aphid, green apple aphid and their natural enemies in an apple organic orchard [PDF]

, 2007
Cover crops have been reported as shelters for pest but also for natural enemies. Nevertheless, there is not agreement about their influence on pest presence on apple trees.
Alegre, Simó, Alins, Georgina, Avilla, Jesús   +2 more
core  

The combined effects of cover design parameters on tomato production of a passive greenhouse [PDF]

, 2008
The objective of this paper is to demonstrate the need of a multiple design parameter approach to greenhouse design. To illustrate this need, we determined the combined effects of cover design parameters on tomato production of a passive greenhouse, that
Gazquez, J.C., Henten, E., van, Stanghellini, C., Vanthoor, B.H.E.   +3 more
core   +2 more sources

The 4Rs for cover crops and other advances in cover crop management for environmental quality [PDF]

Journal of Soil and Water Conservation, 2015
H umans have used soil resources for thousands of years. Human use has degraded and eroded soil worldwide in ways that damage food production, biodiversity, and ecosystem services. A direct implication of soil degradation is that soil scarcity will become a critical future problem for global agricultural production.
Jorge A. Delgado, Clark J. Gantzer
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Cover Crop Mixture Effects on Maize, Soybean, and Wheat Yield in Rotation

Agricultural & Environmental Letters, 2019
Despite the popularity of multispecies cover crop mixtures, there is little published evidence of their effects on subsequent crop yields, especially for multiple crops grown in rotation.
Mitchell C. Hunter, Meagan E. Schipanski, Macdonald H. Burgess, James C. LaChance, Brosi A. Bradley, Mary E. Barbercheck, Jason P. Kaye, David A. Mortensen   +7 more
doaj   +1 more source

Increased Productivity of a Cover Crop Mixture Is Not Associated with Enhanced Agroecosystem Services [PDF]

, 2014
Cover crops provide a variety of important agroecological services within cropping systems. Typically these crops are grown as monocultures or simple graminoid-legume bicultures; however, ecological theory and empirical evidence suggest that ...
Atwood, Lesley W., Smith, Richard G., Warren, Nicholas D.   +2 more
core   +3 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source