Results 71 to 80 of about 1,621,757 (315)

The History of the Creation and Semantics of the Sacred Space of Ust-Medveditskiy Convent Caves in Volgograd Region

Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019
Introduction. The article presents the caves of Ust-Medveditsky St. Saviour convent in Volgograd region. The relevance of the research issue is in improving the recreational potential of the subject under study.
Vitaliy V. Stepkin
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Developing a Trauma System Improvement Program (TSIP) in Bangladesh: findings from a pilot study

BMC Emergency Medicine
Introduction The Trauma System Improvement Program (TSIP) plays a crucial role in improving trauma care outcomes. Despite its importance, the development and implementation of a hospital-based TSIP for road traffic injury (RTI) victims has received ...
Zarin Tasnim, Md Karimuzzaman, Nahitun Naher, Bushra Zarin Islam, Samiun Nazrin Bente Kamal Tune, Amber Mehmood, Suresh Kunhi Mohammed, S. M. Asib Nasim, Rafi Hossain, Syed Masud Ahmed   +9 more
doaj   +1 more source

Investigating the Relationship Between Topographic Variables and Wildfire Burn Severity

Geographies
Wildfire behavior and post-fire effects are strongly modulated by terrain, yet the relative influence of individual topographic factors on burn severity remains incompletely quantified at landscape scales.
Linh Nguyen Van, Giha Lee
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Knowledge, attitudes, and practices on antibiotic use and resistance among adolescents and young people in Sierra Leone: a cross-sectional study

BMC Public Health
Background The studies on knowledge, attitudes, and practices of Antimicrobial resistance (AMR) and use among adolescents and young people are largely from Europe and the Asia region.
Ibrahim Franklyn Kamara, Sia Morenike Tengbe, Patricia Abu, Binyam Hailu, Tumisang Malebo Madisa, Bobson Derrick Fofanah, Fatmata Bintu Kargbo, Bintu Mansaray, Pruthu Thekkur, Mariama Mustapha, Massimo Sartelli, Yahaya Ali Ahmed, George Ameh   +12 more
doaj   +1 more source

Coverage of the infected wound

Plastic and Reconstructive Surgery, 1983
Fifty-four consecutive patients with chronic wounds were identified by the following criteria: (1) established infection for 6 months, (2) exposure of bone, mediastinum, or other vital structure, (3) mechanical and/or vascular limitations to delayed closure techniques, (4) no response to wound debridement in prolonged antibiotic therapy.
S J, Mathes, L J, Feng, T K, Hunt
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

International news coverage in the United States media [PDF]

, 2003
Thesis Chair, Dr. Sue Wildermuth. This file was last viewed in Adobe Reader 7.0United States media has the power to enlighten the American public about other countries. The media, however, chooses to portray a distorted picture.
Ortiz Vazquez, Vickie M.
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