Results 71 to 80 of about 1,107,469 (269)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Health policy, collaboration and investment in the post-COVID era: a review from UHC and health security integration perspective

open access: yesGlobalization and Health
Background The COVID-19 pandemic exposed weaknesses in health systems globally, highlighting chronic underinvestment, fragmentation, and a lack of preparedness with catastrophic impact on public health, economies and societies.
Sohel Saikat   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Secrecy coverage [PDF]

open access: yes2010 Conference Record of the Forty Fourth Asilomar Conference on Signals, Systems and Computers, 2010
Amites Sarkar, Martin Haenggi
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Determinants of incomplete vaccination against polio by 2 years of age in Canada: A cross-sectional study using the Childhood National Immunization Coverage Survey (CNICS)

open access: yesVaccine: X
Background: Canada has not reached the national vaccination coverage goal of 95 % for polio vaccination in 2-year-old children. The objective of this study was to examine determinants of incomplete polio vaccination (receipt of less than 3 doses of a ...
Israa Zareef   +4 more
doaj   +1 more source

WHO urges “coverage for all, not coverage of everything”

open access: yesBMJ, 1999
Governments must ensure that good health care is accessible to everyone, but they should not attempt to provide all possible treatments, according to the World Health Organisation's annual report. The report was launched this week as the UN agency's member states gather for their annual assembly on 17 May.
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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