Results 71 to 80 of about 3,733,183 (293)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Developing a Trauma System Improvement Program (TSIP) in Bangladesh: findings from a pilot study

BMC Emergency Medicine
Introduction The Trauma System Improvement Program (TSIP) plays a crucial role in improving trauma care outcomes. Despite its importance, the development and implementation of a hospital-based TSIP for road traffic injury (RTI) victims has received ...
Zarin Tasnim, Md Karimuzzaman, Nahitun Naher, Bushra Zarin Islam, Samiun Nazrin Bente Kamal Tune, Amber Mehmood, Suresh Kunhi Mohammed, S. M. Asib Nasim, Rafi Hossain, Syed Masud Ahmed   +9 more
doaj   +1 more source

Investigating the Relationship Between Topographic Variables and Wildfire Burn Severity

Geographies
Wildfire behavior and post-fire effects are strongly modulated by terrain, yet the relative influence of individual topographic factors on burn severity remains incompletely quantified at landscape scales.
Linh Nguyen Van, Giha Lee
doaj   +1 more source

Job-based Coverage Drops for Adults and Children but Public Programs Boost Children's Coverage [PDF]

, 2005
Provides a profile of non-elderly Californians' health insurance coverage and lack of coverage, and describes how these rates have changed. Estimates the number of children and adults who are uninsured but eligible for coverage through public ...
E. Richard Brown, Shana Alex Lavarreda
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Knowledge, attitudes, and practices on antibiotic use and resistance among adolescents and young people in Sierra Leone: a cross-sectional study

BMC Public Health
Background The studies on knowledge, attitudes, and practices of Antimicrobial resistance (AMR) and use among adolescents and young people are largely from Europe and the Asia region.
Ibrahim Franklyn Kamara, Sia Morenike Tengbe, Patricia Abu, Binyam Hailu, Tumisang Malebo Madisa, Bobson Derrick Fofanah, Fatmata Bintu Kargbo, Bintu Mansaray, Pruthu Thekkur, Mariama Mustapha, Massimo Sartelli, Yahaya Ali Ahmed, George Ameh   +12 more
doaj   +1 more source

The Uninsured at the Starting Line: Findings from the 2013 Kaiser Survey of Low-Income Americans and the ACA [PDF]

, 2014
In January 2014, the major coverage provisions of the 2010 Affordable Care Act (ACA) went into full effect. These provisions include the creation of new Health Insurance Marketplaces where low and moderate income families can receive premium tax credits ...
Katherine Young, Rachel Garfield, Rachel Licata   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Children's Health Coverage Facts and Figures [PDF]

, 2009
Outlines trends in children's health insurance in California. Reviews 1997-2009 milestones in expanding coverage and examines uninsurance rates; eligibility for and enrollment in public programs; sources of coverage by income and age; and access to ...
Dana Hughes, Michael R. Cousineau
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source