Results 111 to 120 of about 66,784,034 (314)

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

Hospitalisations and Deaths Averted by COVID-19 Vaccination in Navarre, Spain, 2021–2022

In 2021–2022, most of the Spanish population received COVID-19 vaccines and a high proportion of them had SARS-CoV-2 infection. We estimated the rate of hospitalisations and deaths that were averted by risk reduction among vaccinated COVID-19 cases.
Ana Navascués, Manuel García Cenoz, Marcela Guevara, Miguel Fernández-Huerta, Nerea Egüés, Iván Martínez-Baz, Itziar Casado, Ana Miqueleiz, Aitziber Echeverría, Carmen Ezpeleta, Camino Trobajo-Sanmartín, Jesús Castilla   +11 more
core   +1 more source

Assessing Doubts, Knowledge, and Service Appreciation among Pregnant Women Who Received the COVID-19 Vaccination in an Italian Research Hospital: A Cross-Sectional Study

, 2023
The COVID-19 pandemic is considered one of the deadliest pandemics in history. Pregnant women are more susceptible to developing serious diseases during COVID-19 than their non-pregnant peers.
Paola Arcaro, Campo, Enrica, Damiani, Gianfranco, Gianfranco Damiani, Chiara Cadeddu, Patrizia Laurenti, Laurenti, Patrizia, Fabio Pattavina, Lanzone, Antonio, Stefania Bruno, Arcaro, Paola, Brigida Carducci, Antonio Lanzone, Nachira, Lorenza, Cadeddu, Chiara, Lorenza Nachira, Enrica Campo, Pattavina, Fabio, Carducci, Brigida, Bruno, Stefania, FPG COVID-19 Vaccination Team (FPG-CVT) FPG COVID-19 Vaccination Team (FPG-CVT)   +20 more
core   +1 more source

Characteristics Associated With Persistent Long COVID Symptoms in Healthcare Personnel Infected With SARS‐CoV‐2 Between August 2022 and May 2024: A Multicenter Cohort Analysis of US Healthcare Personnel

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Long COVID affects a significant proportion of COVID‐19 survivors. This study examined persistent Long COVID symptoms among healthcare personnel (HCP) and evaluated associations with vaccination, prior SARS‐CoV‐2 infection, underlying health conditions, and demographics.
Eric Kontowicz, Amanda K. Irish, Lilly C. Lee, Howard A. Smithline, Ian D. Plumb, Melissa Briggs‐Hagen, Alexandra F. Rollins, Karisa K. Harland, Anusha Krishnadasan, Karin F. Hoth, Eliezer Santos‐León, David A. Talan, Nicholas M. Mohr, Project PREVENT Network   +13 more
wiley   +1 more source

Association between vaccination beliefs and COVID-19 vaccine uptake in a longitudinal panel survey of adults in the United States, 2021–2022

Vaccine: X
COVID-19 vaccine hesitancy has been a major limiting factor to the widespread uptake of COVID-19 vaccination in the United States. A range of interventions, including mass media campaigns, have been implemented to encourage COVID-19 vaccine confidence ...
Elissa C. Kranzler, Joseph N. Luchman, Katherine A. Margolis, Timothy O. Ihongbe, Jae-Eun C. Kim, Benjamin Denison, Victor Vuong, Blake Hoffman, Heather Dahlen, Kathleen Yu, Daphney Dupervil, Leah Hoffman   +11 more
doaj   +1 more source

Varicella Zoster Virus Reactivation Following COVID-19 Vaccination: A Systematic Review of Case Reports

, 2021
The newly developed COVID-19 vaccines have established a safe profile, yet some individuals experience a wide range of adverse events. Recently, reactivation of varicella zoster virus (VZV) has been observed after administration of different COVID-19 ...
Panagiotis Giannos, Konstantinos Katsikas Triantafyllidis, George Kyrtsonis, Konstantinos S. Kechagias, Imran Tariq Mian   +4 more
core   +1 more source

Covid-19 vaccines for kids

New Scientist, 2021
Early trial results hint that vaccines could be safe for children, but how the virus behaves will determine their roll-out, reports Helen Thomson.
openaire   +2 more sources

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

Advanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir, Shuxiong Chen, Justine B. Bendo, Ashley Johnson, Aleksandra W. Debowski, Mitali Sarkar‐Tyson, Bernd H. A. Rehm   +6 more
wiley   +1 more source

Dose Intervals and Time since Final Dose on Changes in Metabolic Indices after COVID-19 Vaccination

, 2023
The rapid development and implementation of COVID-19 vaccines merit understanding its effects on metabolic indices. This retrospective longitudinal study investigated the influence of first-to-second-dose intervals and time since the final dose on the ...
Nasser M. Al-Daghri, Abdullah M. Alnaami, Amani Alghamdi, Kaiser Wani   +3 more
core   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source