Results 101 to 110 of about 312,011 (322)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

SARS-CoV-2 vaccine candidates in rapid development

Human Vaccines & Immunotherapeutics, 2021
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still spreading globally. The scientific community is attempting to procure an effective treatment and prevention strategy for COVID-19.
Lifeng Li, Pengbo Guo, Xiaoman Zhang, Zhidan Yu, Wancun Zhang, Huiqing Sun   +5 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Understanding the content of COVID-19 vaccination and pregnancy videos on YouTube: An analysis of videos published at the start of the vaccine rollout [PDF]

, 2022
Priscila E Laforet, Corey H. Basch, Hao Tang   +2 more
openalex   +1 more source

COVID‐19 despite full COVID‐19 vaccination [PDF]

Transplant Infectious Disease, 2021
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit   +1 more
openaire   +2 more sources

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Time for action: towards an intersectional gender approach to COVID-19 vaccine development and deployment that leaves no one behind

BMJ Global Health, 2021
Folake Olayinka, Sonali Kochhar, Shirin Heidari, Ruth Faden, Noni MacDonald, Tracey S Goodman   +5 more
doaj   +1 more source

GAMBARAN TINGKAT KECEMASAN ORANG DEWASA YANG BELUM MENJALANI VAKSINASI COVID-19 [PDF]

, 2023
The continuously widespread of the Covid-19 virus, the high death rate, and the large number of people who have not been vaccinated have raised concerns about the risk of dangerous disease.
Putri, Wahyu Ananda
core  

Decoding SARS-CoV-2 Transmission and Evolution and Ramifications for COVID-19 Diagnosis, Vaccine, and Medicine [PDF]

, 2020
Rui Wang, Yuta Hozumi, Changchuan Yin, Guo‐Wei Wei   +3 more
openalex   +1 more source

Knowledge, Attitude, and Acceptance of Sinopharm and AstraZeneca’s COVID-19 Vaccines among Egyptian Population: A Cross-Sectional Study [PDF]

, 2022
Marian S. Boshra, Marwa O. Elgendy, Lamiaa N. Abdelaty, Mahmoud Tammam, Abdullah Salah Alanazi, Abdulaziz Ibrahim Alzarea, Saud Alsahali, Rania M. Sarhan   +7 more
openalex   +1 more source