Results 121 to 130 of about 288,867 (293)
Animal Models and Experimental Medicine, EarlyView.Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma +2 more
wiley +1 more source
Humanized immune system animal models and their recent applications
Animal Models and Experimental Medicine, EarlyView.In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli +6 more
wiley +1 more source
Modelling the spread of Covid19 in Italy using a revised version of the SIR model
, 2020 In this paper, we present a model to predict the spread of the Covid-19 epidemic and apply it to the specific case of Italy. We started from a simple Susceptible, Infected, Recovered (SIR) model and we added the condition that, after a certain time, the ...
Atzeni, Luigi Giuseppe +7 more
core +1 more source
Pakistan Journal of Medical Research, 2023 The highly contagious SARS-CoV-2, (COVID-19), has put huge pressure on the health-care system worldwide. In order to trick the immune system into producing response different vaccines with varying technologies have been developed. In Pakistan so far around seven different Covid-19 vaccines are being administered. 1 Most of the vaccines are designed for
openaire +3 more sources
The United States Leads the Globe in Venture Capital Funding for Orthopaedic Surgery
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To characterize venture capital (VC) investments in orthopaedic surgery over the past 25 years to evaluate trends in global innovation. Methods All VC investments related to orthopaedic surgery between January 2000 and December 2024 were retrospectively evaluated using the PitchBook database (PitchBook Platform, PitchBook Data.
Mathangi Sridharan +7 more
wiley +1 more source
Development of allergy in children. I. Association with virus infections. [PDF]
, 1979 Children born into allergic families, with two allergic parents, are at high risk of developing allergy within the first 5 years of life. In order to observe possible external factors in the sensitization process, a prospective study of 13 such children ...
Frick, OL, German, DF, Mills, J
core
COVID-19 Infection: Implications for Perioperative and Critical Care Physicians. [PDF]
, 2020 Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19), an emerging infectious syndrome caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. Patients with COVID-19 can progress from asymptomatic or
Greenland, John R +3 more
core
Arthritis &Rheumatology, Accepted Article.Background Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post‐acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel +18 more
wiley +1 more source