Intrabronchial inoculation of cynomolgus macaques with cowpox virus
The public health threat of orthopoxviruses from bioterrorist attacks has prompted researchers to develop suitable animal models for increasing our understanding of viral pathogenesis and evaluation of medical countermeasures (MCMs) in compliance with the FDA Animal Efficacy Rule.
Alvin L, Smith +7 more
openaire +2 more sources
Study of Vaccinia and Cowpox viruses' replication in Rac1-N17 dominant-negative cells
Interfering with cellular signal transduction pathways is a common strategy used by many viruses to create a propitious intracellular environment for an efficient replication.
Ana Paula Carneiro Salgado +6 more
doaj +1 more source
The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors. [PDF]
Iyer RF +10 more
europepmc +1 more source
Rats, Mice, and People: Rodent Biology and Management [PDF]
Farm Management,
Anonymous +3 more
core +1 more source
The neutralization of pox viruses II. Relationships betweenvaccinia, rabbitpox, cowpox and ectromelia [PDF]
T. A. McNeill
openalex +1 more source
An anti-poxvirus vaccine based on replicon particles of Venezuelan equine encephalitis virus (VRP) is being developed. The cowpox virus genes encoding structural proteins corresponding to vaccinia virus proteins A33, B5, and A27 were each expressed from VRP. High serum IgG titers against these proteins were generated in BALB/c mice vaccinated with each
Thornburg, Natalie J. +5 more
openaire +2 more sources
Novel Orthopoxvirus and Lethal Disease in Cat, Italy
We report detection and full-genome characterization of a novel orthopoxvirus (OPXV) responsible for a fatal infection in a cat. The virus induced skin lesions histologically characterized by leukocyte infiltration and eosinophilic cytoplasmic inclusions.
Gianvito Lanave +10 more
doaj +1 more source
Direct Priming of CD8+ T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation. [PDF]
Lin LCW +7 more
europepmc +1 more source
Structural mechanism of ER retrieval of MHC class I by cowpox.
One of the hallmarks of viral immune evasion is the capacity to disrupt major histocompatibility complex class I (MHCI) antigen presentation to evade T-cell detection.
William H McCoy +4 more
doaj +1 more source
Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. [PDF]
Shchelkunov SN +11 more
europepmc +1 more source

