Results 111 to 120 of about 10,225 (252)

Intrabronchial inoculation of cynomolgus macaques with cowpox virus

open access: yesJournal of General Virology, 2012
The public health threat of orthopoxviruses from bioterrorist attacks has prompted researchers to develop suitable animal models for increasing our understanding of viral pathogenesis and evaluation of medical countermeasures (MCMs) in compliance with the FDA Animal Efficacy Rule.
Alvin L, Smith   +7 more
openaire   +2 more sources

Study of Vaccinia and Cowpox viruses' replication in Rac1-N17 dominant-negative cells

open access: yesMemorias do Instituto Oswaldo Cruz, 2013
Interfering with cellular signal transduction pathways is a common strategy used by many viruses to create a propitious intracellular environment for an efficient replication.
Ana Paula Carneiro Salgado   +6 more
doaj   +1 more source

The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors. [PDF]

open access: yesPLoS Pathog, 2022
Iyer RF   +10 more
europepmc   +1 more source

Rats, Mice, and People: Rodent Biology and Management [PDF]

open access: yes
Farm Management,
Anonymous   +3 more
core   +1 more source

Vaccination with Venezuelan equine encephalitis replicons encoding cowpox virus structural proteins protects mice from intranasal cowpox virus challenge

open access: yesVirology, 2007
An anti-poxvirus vaccine based on replicon particles of Venezuelan equine encephalitis virus (VRP) is being developed. The cowpox virus genes encoding structural proteins corresponding to vaccinia virus proteins A33, B5, and A27 were each expressed from VRP. High serum IgG titers against these proteins were generated in BALB/c mice vaccinated with each
Thornburg, Natalie J.   +5 more
openaire   +2 more sources

Novel Orthopoxvirus and Lethal Disease in Cat, Italy

open access: yesEmerging Infectious Diseases, 2018
We report detection and full-genome characterization of a novel orthopoxvirus (OPXV) responsible for a fatal infection in a cat. The virus induced skin lesions histologically characterized by leukocyte infiltration and eosinophilic cytoplasmic inclusions.
Gianvito Lanave   +10 more
doaj   +1 more source

Direct Priming of CD8+ T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation. [PDF]

open access: yesJ Virol, 2021
Lin LCW   +7 more
europepmc   +1 more source

Structural mechanism of ER retrieval of MHC class I by cowpox.

open access: yesPLoS Biology, 2012
One of the hallmarks of viral immune evasion is the capacity to disrupt major histocompatibility complex class I (MHCI) antigen presentation to evade T-cell detection.
William H McCoy   +4 more
doaj   +1 more source

Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. [PDF]

open access: yesViruses, 2021
Shchelkunov SN   +11 more
europepmc   +1 more source

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