Results 141 to 150 of about 714,188 (330)
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard+15 more
wiley +1 more source
Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget+7 more
wiley +1 more source
Background and purpose: One of the major problems in chemotherapy is resistance to anti-cancer drugs. Recent studies have demonstrated a relationship between cyclooxygenase-2 (COX-2) expression and progression of multidrug resistance (MDR).
Saeedeh Vahedi+4 more
doaj
An inhibitory effect of meloxicam, a novel nonsteroidal anti-inflammatory drug, on COX-2.
Keiko Ogino+6 more
openalex +1 more source
Room A, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Single Dose Tolerability and Pharmacokinetics of Parecoxib Sodium, a COX-2 Specific Inhibitor, Following Intravenous Administration [PDF]
Aziz Karim+4 more
openalex +1 more source
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker+9 more
wiley +1 more source
High cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) contents in mouse lung tumors [PDF]
Alison K. Bauer+2 more
openalex +1 more source
COX-2 mRNA Expression is Significantly Increased in Acid-exposed Compared to Nonexposed Squamous Epithelium in Gastroesophageal Reflux Disease [PDF]
Background: Little is known about the role of cyclooxygenase (COX)-2 in gastroesophageal reflux disease (GERD) and the development of Barrett's metaplasia.
Baldus, Stephan+11 more
core
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. While pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen+4 more
wiley +1 more source