Results 251 to 260 of about 714,188 (330)

Exploring the potential of <i>Laportea decumana</i> extract compounds as COX-1 and COX-2 inhibitors: An in silico study. [PDF]

Narra J
Simaremare ES, Kurniawan F, Hartati R, Tjahjono DH.   +3 more
europepmc   +1 more source

Effect of a selective COX-2 non-steroidal anti-inflammatory on the small bowel

, 2000
Andre Za Leite, Aytan Miranda Sipahi, Aderson Omc Damiao, Fábio Pinatel Lopasso, Alexandre Teles Garcez, Carlos A. Buschipiguel, Maria Laura Lacava Lordello, Carmen Lo Agostinho, Antônio Atílio Laudanna   +8 more
openalex   +1 more source

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

Advanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang, Linyu Han, Yanfei Huo, Long Zhang, Yizhou Huang, Nasha Zhang, Ming Yang   +6 more
wiley   +1 more source

PAO1: COST-EFFECTIVENESS ANALYSIS OF NSAIDS VS COX-2 SPECIFIC INHIBITORS AND NSAIDS WITH CO-TREATMENTS TO PREVENT Gl TOXICITY IN THE TREATMENT OF RA

, 2000
HR Yun, Michael Corzillius, SY Kim, Sang‐Cheol Bae   +3 more
openalex   +1 more source

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

Advanced Science, EarlyView.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, Martina Morini, Martina Ardito, Alessandra Eva, Vincenza Cerbone, Lucia Mauriello, Marianna Caterino, Margherita Ruoppolo, John M. Maris, Sharon J. Diskin, Achille Iolascon, Mario Capasso   +20 more
wiley   +1 more source

Pharmacological investigations of newly synthesized oxazolones and imidazolones as COX-2 inhibitors. [PDF]

Saudi Pharm J
Saleem Naz Babari I, Islam M, Saeed H, Nadeem H, Anwer Rathore H.   +4 more
europepmc   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea. [PDF]

Front Immunol
Song Y, Ni J, Yuan J, Zhang Z, Wang D, Xiong Z.   +5 more
europepmc   +1 more source

Lansoprazole induces mucosal protection through gastrin/CCK-B receptor-dependent upregulation of COX-2 in rats

, 2000
Wei‐Hao Sun, Shingo Tsuji, Masahiko Tsujii, Edhi S. Gunawan, Arata Kimura, Yutaka Sasaki, Masatsugu Hori, Sunao Kawano   +7 more
openalex   +1 more source