Results 61 to 70 of about 755,483 (324)

MicroRNA MiR-21 and MiR-155 are new markers for breast cancer

Опухоли женской репродуктивной системы, 2014
In the cell there is a large class of regulatory molecules referred to as microRNA. Many investigators regard microRNA Mir and Mir-155 as new potential prognostic markers and targets for goal-oriented therapy for breast cancer (BC) these days. MiR-21 and
M. A. Taipov, Z. N. Nikiphorova, K. P. Laktionov, N. E. Levchenko, V. E. Shevchenko   +4 more
doaj   +1 more source

The Role of Prostaglandins in Different Types of Cancer

Cells, 2021
The prostaglandins constitute a family of lipids of 20 carbon atoms that derive from polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have been linked to inflammation, female reproductive cycle, vasodilation, or ...
Álvaro Jara-Gutiérrez, Victoriano Baladrón   +1 more
doaj   +1 more source

COX-2 disruption leads to increased central vasopressin stores and impaired urine concentrating ability in mice [PDF]

, 2011
It was hypothesized that cyclooxygenase-2 (COX-2) activity promotes urine concentrating ability through stimulation of vasopressin (AVP) release after water deprivation (WD).
Bie, Peter, Frøkiær, Jørgen, Hansen, Pernille B L, Jensen, Boye L, Madsen, Kirsten, Nørregaard, Rikke, Thavalingam, Sugarna   +6 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells

Опухоли женской репродуктивной системы, 2014
The expression of СOX-2, VEGF, VEGFR-1, VEGFR-2, VEGFR-3, EGFR, endoglin (СD105), and IL-6 was analyzed in the human breast tumor cells having a varying metastatic potential.
M. A. Taipov, Z. N. Nikiforova, I. A. Kudryavtsev, N. Ye. Arnotskaya, V. Ye. Shevchenko   +4 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

5-PGDH expression in breast cancer cells

Опухоли женской репродуктивной системы, 2014
This paper analyzes 15-PGDH gene expression in the human breast cancer (BC) cell liness and describes the molecular principles through which the expression of the enzyme 15-PGDH is controlled in the tumor cells with a varying metastatic potential.
M. A. Taipov, Z. N. Nikiforova, O. M. Pavlova, I. A. Kudryavtsev, N. Ye. Arnotskaya, V. Ye. Shevchenko   +5 more
doaj   +1 more source

Protective effects of total flavonoids from Alpinia officinarum rhizoma against ethanol-induced gastric ulcer in vivo and in vitro

Pharmaceutical Biology, 2020
Context Alpinia officinarum Hance (Zingiberaceae) is traditionally used to treat inflammation, pain, colds and digestive diseases. Objective To investigate the potential protective mechanism of total flavonoids from the rhizomes of A. officinarum (F-AOH)
Kaiwen Lin, Yong Wang, Jingwen Gong, Yinfeng Tan, Tang Deng, Na Wei   +5 more
doaj   +1 more source

Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention [PDF]

, 2010
Background Low-dose aspirin reduces the incidence of colorectal cancer and recurrence of adenomas. Cyclooxygenase-2 (COX-2), one of its main target enzymes, is reportedly over-expressed in colorectal adenomas.Aim To assess COX-2 expression, in relation ...
A. Martin, Association pour la Prévention par l\u27Aspirine du Cancer Colorectal Study Group, B. Girard, B. Uzzan, J. Deyra, J. Little, R. Benamouzig, S. Chaussade   +7 more
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source