Results 31 to 40 of about 614,587 (286)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RisksThe development of health indicators to measure healthy life expectancy (HLE) is an active field of research aimed at summarizing the health of a population.
Oleksandr Sorochynskyi +3 more
doaj +1 more source
Cox model and decision trees: an application to breast cancer data
Revista Panamericana de Salud Pública, 2022 Objective. To evaluate, using semiparametric methodologies of survival analysis, the relationship between covariates and time to death of patients with breast cancer, as well as the determination discriminatory power in the conditional inference tree of ...
Lucas Cardoso Pereira +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Estimation of Employee Turnover with Competing Risks Models
Folia Oeconomica Stetinensia, 2015 Employee turnover accompanies every business organization, regardless of the industry and size. Nowadays, many companies struggle with problems related to the lack of sufficient information about the nature of employee turnover processes.
Grzenda Wioletta, Buczyński Michał K.
doaj +1 more source
Stepwise cox regression analysis in SPSS
Cancer Research, Statistics, and Treatment, 2018 This article is a beginners' guide for performing Cox regression analysis in SPSS. The article provides practical steps toward performing Cox analysis and interpreting the output of SPSS for Cox regression analysis.
Sampada Dessai, Vijai Simha, Vijay Patil
doaj +1 more source
Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]
, 2003 This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Blettner, Maria +3 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Recurrent events and the exploding Cox model [PDF]
Lifetime Data Analysis, 2010 Counting process models have played an important role in survival and event history analysis for more than 30 years. Nevertheless, almost all models that are being used have a very simple structure. Analyzing recurrent events invites the application of more complex models with dynamic covariates. We discuss how to define valid models in such a setting.
Gjessing, Håkon K. +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source