Results 51 to 60 of about 537,274 (264)
Subgroup Discovery with the Cox Model
CoRR43 pages, 2 ...
Zachary Izzo, Iain Melvin
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Stratified Cox Model with Interactions in Analysis of Recurrent Events
Acta Universitatis Lodziensis. Folia Oeconomica, 2018 The purpose of this paper is the assessment of relative intensity of exit from registered unemployment by means of the analysis of recurrent survival episodes and the comparison of these results with the results obtained for an individual episode.
Beata Bieszk‑Stolorz
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Bias Of The Cox Model Hazard Ratio [PDF]
Journal of Modern Applied Statistical Methods, 2005 In recent decades, survival analysis techniques have been extended far beyond the medical, biomedical, and reliability research areas to fields such as engineering, criminology, sociology, marketing, insurance, economics, etc. The study of survival data has previously focused on predicting the probability of response, survival, or mean lifetime, and ...
Persson, Inger, Khamis, Harry J.
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A Cox Model-Based Workflow for Increased Accuracy in Activity-Travel Patterns Generation
Applied SciencesUnderstanding how people spend time on daily activities is key to modeling travel behavior. However, accurately estimating the duration of these activities remains a significant challenge, especially when generating synthetic activity-travel data.
Dionysios Katsaitis +2 more
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Наука и инновации в медицинеAim – to compare the predictive accuracy of Cox regression and machine learning (ML) methods regarding recurrence-free survival in patients with locally advanced renal cell carcinoma after radical treatment.
Musabek K. Mirzabekov +4 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source