Results 61 to 70 of about 614,587 (286)

Cox-Snell residual to check proportional hazard model fitness.

, 2022
Cox-Snell residual to check proportional hazard model fitness.
Andamlak Eskale Mebratie (12937104), Misganaw Fikrie Melesse (11302437), Nurilign Abebe Moges (8715573), Belsity Temesgen Meselu (12937107)   +3 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Stratified Cox Model with Interactions in Analysis of Recurrent Events

Acta Universitatis Lodziensis. Folia Oeconomica, 2018
The purpose of this paper is the assessment of relative intensity of exit from registered unemployment by means of the analysis of recurrent survival episodes and the comparison of these results with the results obtained for an individual episode.
Beata Bieszk‑Stolorz
doaj   +1 more source

Expression of COX-1 and COX-2 in a Clinical Model of Acute Inflammation [PDF]

The Journal of Pain, 2007
Cyclooxygenase (COX) plays an important role in the induction of pain and inflammation as well as the analgesic actions of NSAIDs and coxibs. This study evaluates the expression of the two isoforms COX-1 and COX-2 in a clinical model in which the surgical removal of impacted third molars is used to evaluate the analgesic activity of anti-inflammatory ...
Asma A, Khan, Michael, Iadarola, Hsiu-Ying T, Yang, Raymond A, Dionne   +3 more
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A Cox Model-Based Workflow for Increased Accuracy in Activity-Travel Patterns Generation

Applied Sciences
Understanding how people spend time on daily activities is key to modeling travel behavior. However, accurately estimating the duration of these activities remains a significant challenge, especially when generating synthetic activity-travel data.
Dionysios Katsaitis, Dimitrios Rizopoulos, Konstantinos Gkiotsalitis   +2 more
doaj   +1 more source

Uncertain Box-Cox Regression Analysis With Rescaled Least Squares Estimation

IEEE Access, 2020
Under the uncertain statistical framework by Liu [19], there is still a lack of an effective fitting method for uncertain linear models with Box-Cox transformation of response variables.
Shiqin Liu, Liang Fang, Zaiying Zhou, Yiping Hong   +3 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Prediction of recurrence-free survival in patients with renal cell carcinoma and tumor thrombosis of the renal and inferior vena cava of levels I–II using an extended Cox model and machine learning methods

Наука и инновации в медицине
Aim – to compare the predictive accuracy of Cox regression and machine learning (ML) methods regarding recurrence-free survival in patients with locally advanced renal cell carcinoma after radical treatment.
Musabek K. Mirzabekov, Nikolai D. Tikhonskii, Mikhail I. Shkolnik, Oleg A. Bogomolov, Nina V. Trukhacheva   +4 more
doaj   +1 more source