Results 11 to 20 of about 14,848,273 (189)

Extension of Cox Proportional Hazard Model for Estimation of Interrelated Age-Period-Cohort Effects on Cancer Survival

open access: yesCancer Informatics, 2011
In the frame of the Cox proportional hazard (PH) model, a novel two-step procedure for estimating age-period-cohort (APC) effects on the hazard function of death from cancer was developed. In the first step, the procedure estimates the influence of joint
Tengiz Mdzinarishvili   +3 more
doaj   +3 more sources

Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]

open access: yesStatistics in Medicine, 2003
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Blettner, Maria   +3 more
core   +5 more sources

The impact of violation of the proportional hazards assumption on the discrimination of the Cox proportional hazards model

open access: yesDiagnostic and Prognostic Research
Background The Cox proportional hazards regression model is frequently used to estimate an individual’s probability of experiencing an outcome within a specified prediction horizon. A key assumption of this model is that of proportional hazards.
Peter C. Austin, Daniele Giardiello
doaj   +3 more sources

Estimation in a Cox Proportional Hazards Cure Model [PDF]

open access: yesBiometrics, 2000
Summary.Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow‐up period, and a standard survival analysis would not always be appropriate.
Sy, Judy P., Taylor, Jeremy M. G.
openaire   +4 more sources

A Federated Cox Model with Non-Proportional Hazards

open access: yesCoRR, 2022
Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally available, whereas healthcare data are frequently held in secure silos.
Dekai Zhang   +2 more
openaire   +3 more sources

Predicting completion of clinical trials in pregnant women: Cox proportional hazard and neural network models

open access: yesClinical and Translational Science, 2022
This study aimed to develop a model for predicting the completion of clinical trials involving pregnant women using the Cox proportional hazard model and neural network model (DeepSurv) and to compare the predictive performance of both methods.
Bomee Kim   +6 more
doaj   +1 more source

Gradient lasso for Cox proportional hazards model [PDF]

open access: yesBioinformatics, 2009
AbstractMotivation: There has been an increasing interest in expressing a survival phenotype (e.g. time to cancer recurrence or death) or its distribution in terms of a subset of the expression data of a subset of genes. Due to high dimensionality of gene expression data, however, there is a serious problem of collinearity in fitting a prediction model,
Insuk Sohn   +3 more
openaire   +2 more sources

Tree-augmented Cox proportional hazards models [PDF]

open access: yesBiostatistics, 2005
We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also ...
Su, Xiaogang, Tsai, Chih Ling
openaire   +4 more sources

Survival time prediction by integrating cox proportional hazards network and distribution function network

open access: yesBMC Bioinformatics, 2021
Background The Cox proportional hazards model is commonly used to predict hazard ratio, which is the risk or probability of occurrence of an event of interest.
Eu-Tteum Baek   +6 more
doaj   +1 more source

A mixed model approach for structured hazard regression [PDF]

open access: yes, 2004
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Thomas Kneib   +4 more
core   +1 more source

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