Results 141 to 150 of about 269,636 (288)

An augmented likelihood approach for the Cox proportional hazards model with interval-censored auxiliary and validated outcome data-with application to the Hispanic Community Health Study/Study of Latinos. [PDF]

Stat Methods Med Res, 2023
Boe LA, Shaw PA.
europepmc   +1 more source

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang, Yunyi Zhang, Xiangyu Meng, Jianli Zhao, Yue Xing, Qian Ouyang, Ning Zhang, Huiping Chen, Nanyan Miao, Erwei Song, Di Huang   +10 more
wiley   +1 more source

MODELLING THE DETERMINANTS OF UNDER-FIVE CHILD MORTALITY RATES USING COX PROPORTIONAL HAZARDS REGRESSION MODEL

, 2021
Muflihah Musa, O. E. Asiribo, H. G. Dikko, Mustofa Usman, Seid Sani   +4 more
openalex   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Cox proportional hazard-model application: Time to cervical cancer screening among women living with HIV in South Africa [PDF]

, 2023
Marcus Hollington
openalex   +1 more source

Tumor‐Informed ctDNA in Guiding First‐Line Immunochemotherapy in Advanced Non‐Small Cell Lung Cancers

Advanced Science, EarlyView.
Tumor‐informed circulating tumor DNA (ctDNA) analysis identifies patients with advanced non‐small cell lung cancer (NSCLC) who benefit from first‐line immunotherapy plus chemotherapy. Longitudinal ctDNA monitoring further reflects therapeutic response and predicts prognosis beyond imaging.
Kailun Fei, Jie Zhao, Jiachen Xu, Jianchun Duan, Chengcheng Li, Wenchuan Xie, Jia Zhong, Guoqiang Wang, Yu Xu, Boyang Sun, Rui Wan, Hua Bai, Qinxiang Guo, Wei Guo, Shangli Cai, Zhijie Wang, Jie Wang   +16 more
wiley   +1 more source

Determinants of infant mortality in Gezira State, sudan: a survival analysis using Cox proportional hazards model

Discover Social Science and Health
Background Infant mortality is a critical indicator of population health, with the highest rates observed in sub-Saharan Africa. This study aims to identify factors associated with infant mortality in Gezira State, Sudan. Methods A cross-sectional survey
Mohammed Omar Musa Mohammed, Dawit G. Ayele, Ahmed Saied Rahama Abdallah, Aziza Ahmed Seneen Mohammed   +3 more
doaj   +1 more source

Survival analysis-part 2: Cox proportional hazards model. [PDF]

Indian J Thorac Cardiovasc Surg, 2021
Deo SV, Deo V, Sundaram V.
europepmc   +1 more source

A Simple Test for the Absence of Covariate Dependence in Hazard Regression Models [PDF]

This paper extends commonly used tests for equality of hazard rates in a two-sample or k-sample setup to a situation where the covariate under study is continuous.
Bhattacharjee, Arnab
core   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source