Results 151 to 160 of about 402,477 (353)

Knee crepitus and osteoarthritis features in young adults following traumatic knee injury

open access: yesArthritis Care &Research, Accepted Article.
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One‐year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years)
Jamon L Couch   +8 more
wiley   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

A Cox Proportional-Hazards Model Based on an Improved Aquila Optimizer with Whale Optimization Algorithm Operators [PDF]

open access: gold, 2022
Ahmed A. Ewees   +6 more
openalex   +1 more source

Electrochemically Driven Tandem In‐Plane Reduction and FeCl3‐ Intercalation of Highly Crystalline Graphene Oxide Thin Films

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a green processing route for high‐performance reduced graphene oxide (rGO) transparent conductive films (TCFs) using highly crystalline Brodie's GO. In‐plane electrochemical reduction forms rGO on insulating substrates without toxic reductants or heat. Subsequent FeCl₃ intercalation enhances conductivity, overcoming the transparency–
Tatsuki Tsugawa   +6 more
wiley   +1 more source

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