Results 181 to 190 of about 402,477 (353)

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Consistent estimation in Cox proportional hazards model with measurement errors and unbounded parameter set [PDF]

, 2018
Alexander Kukush, Oksana Chernova
openalex   +1 more source

Evaluation of instrumental variable method using Cox proportional hazard model in epidemiological studies [PDF]

, 2023
Md Jamal Uddin, Tanvir Ahammed, A.Z.M. Hasan Kabir   +2 more
openalex   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Spike-and-slab type variable selection in the Cox proportional hazards model for high-dimensional features. [PDF]

J Appl Stat, 2022
Wu R, Ahn M, Yang H.
europepmc   +1 more source

Resampled Cox Proportional Hazards Models for Infant Mortality at the Kigali University Teaching Hospital [PDF]

, 2019
Paul Gatabazi, Sileshi Fanta Melesse, Shaun Ramroop   +2 more
openalex   +1 more source

Lifestyle and heritability effects on cancer in Bangladesh: an application of Cox proportional hazards model

, 2021
Mst. Farzana Akter, Shahnaj Sultana Sathi, Sabikunnaher Mitu, Mohammad Ohid Ullah   +3 more
openalex   +2 more sources

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

Relative Performance of Model Selection Criteria for Cox Proportional Hazards Regression Based on Kullback’s Symmetric Divergence

Journal of Probability and Statistics
The Cox proportional hazards model is one of the most used models to analyze time-to-event outcomes. The decision on the most suitable model for those data is an essential analysis point.
Clarisse Houénafa Dete, Bruno Enagnon Lokonon, Kossi Essona Gneyou, Marcel Senou, Romain Glèlè Kakaï   +4 more
doaj   +1 more source

IMPACT OF IGNORING PROGNOSTIC FACTORS ON THE ESTIMATE OF TREATMENT EFFECT USING COX PROPORTIONAL HAZARDS MODEL.

, 2006
NULL AUTHOR_ID
openalex   +1 more source