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Mediation analysis with causally ordered mediators using Cox proportional hazards model

Statistics in Medicine, 2018
Causal mediation analysis aims to investigate the mechanism linking an exposure and an outcome. However, studies regarding mediation effects on survival outcomes are limited, particularly in multi‐mediator settings.
Shu-Hsien Cho, Yen-Tsung Huang
semanticscholar   +1 more source

Survival Analysis with Cox Proportional Hazards Model in Predicting Patient Outcomes

International Conference Electronic Systems, Signal Processing and Computing Technologies [ICESC-]
Survival analysis is crucial for understanding the factors that influence patient outcomes across time. The objective is to predict the outcomes of patient survival under various circumstances using the Cox Proportional Hazards Model. The main objectives
Monikapreethi S K   +5 more
semanticscholar   +1 more source

Models of Cox’s Proportional Hazards

Mathematica Applicanda, 2011
The paper presents Cox proportional hazards model, its properties and methods of its parameters estimation. It is widely applicable in survival analysis – in prediction of survival chances of some objects (usually patients in medical studies). The essential advantage of the model is allowing of incomplete data, which often appear in studies – both in ...
openaire   +2 more sources

Competing risk and the Cox proportional hazard model

Journal of Statistical Planning and Inference, 2006
We propose a heuristic for evaluating model adequacy for the Cox proportional hazard model by comparing the population cumulative hazard with the baseline cumulative hazard. We illustrate how recent results from the theory of competing risk can contribute to analysis of data with the Cox proportional hazard model.
Oswald Morales-Napoles, Roger M. Cooke
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Assessment of local influence on Cox’s proportional hazards model

Acta Mathematicae Applicatae Sinica, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Wu Xizhi, Jiang Jiancheng
openaire   +3 more sources

Functional Form Diagnostics for Cox's Proportional Hazards Model

Biometrics, 2004
Summary. We propose a new type of residual and an easily computed functional form test for the Cox proportional hazards model. The proposed test is a modification of the omnibus test for testing the overall fit of a parametric regression model, developed byStute, González Manteiga, and Presedo Quindimil(1998,Journal of the American Statistical ...
Chih-Ling Tsai, Larry F. Leon
openaire   +3 more sources

An application of the cox proportional hazards model to bank failure

Journal of Banking & Finance, 1986
The purpose of this study is to present the Cox proportional hazards model and to apply this model to the prediction of bank failures. The Cox model, which has been used extensively in biomedical applications, has not been previously employed in the finance literature.
W. R. Lane, S. Looney, James W. Wansley
semanticscholar   +3 more sources

Transient effects in the cox proportional hazards regression model

Statistics in Medicine, 1995
AbstractWe consider a model for mortality rates that includes both the long and short term effects of switching from an initial to a second state, for example, when patients receive an initial treatment and then switch to a second treatment. We include transient effects associated with the switch in the model through the use of time‐dependent ...
Friedrich K. Port   +2 more
openaire   +2 more sources

Penalized and Shrinkage Estimation in the Cox Proportional Hazards Model

Communications in Statistics - Theory and Methods, 2014
This article considers the shrinkage estimation procedure in the Cox's proportional hazards regression model when it is suspected that some of the parameters may be restricted to a subspace. We have developed the statistical properties of the shrinkage estimators including asymptotic distributional biases and risks.
S. Hossain, S. E. Ahmed
semanticscholar   +3 more sources

Comparing two crossing hazard rates by Cox proportional hazards modelling

Statistics in Medicine, 2006
AbstractMotivated by a clinical trial of zinc nasal spray for the treatment of the common cold, we consider the problem of comparing two crossing hazard rates. A comprehensive review of the existing methods for dealing with the crossing hazard rates problem is provided.
Jun Sheng, Peihua Qiu, Kejian Liu
openaire   +3 more sources

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