Results 121 to 130 of about 829,002 (272)

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Prognostic determinants and mortality risk of advanced schistosomiasis revealed by Lasso-Cox regression integrative approach. [PDF]

PLoS Negl Trop Dis
Hong Z, Li Y, Zhang S, Xu X, Liu T, Chen Q, Xu J.   +6 more
europepmc   +1 more source

Multivariable analysis with marginal Cox regression analysis for the risk factors of phlebitis stratified by the duration of catheter dwelling.

Yutaro Shinzato (18833161), Hideto Yasuda (4711122), Takashi Moriya (11481485), Haruka Taira (13929918), Yuki Kishihara (9950347), Masahiro Kashiura (3579083), Yuki Kotani (9950344), Natsuki Kondo (9950350), Kosuke Sekine (9950353), Nobuaki Shime (4669279), Keita Morikane (9950356)   +10 more
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Dynamic Clinical and Laboratory Predictors of in-Hospital Mortality in COVID-19: A Multivariate Cox Regression Study. [PDF]

Biomedicines
Arabadzhiyska D, Deneva T, Stefanov R, Stoencheva S.   +3 more
europepmc   +1 more source

Überlebenszeitanalyse: Die Cox-Regression [PDF]

DMW - Deutsche Medizinische Wochenschrift, 2007
A Ziegler, S Lange, R Bender
openaire   +1 more source

Bivariate and Multivariate Cox regression analysis for the predictors of phlebitis among admitted patients with PIVC in DMCSH, 2025(N-372).

Zinaw Beyene (22560121), Haymanot Zeleke Mitiku (22560124), Tesfahun Ayenew (22560127), Mengistu Abebe (22560130), Mihret Kefie (22560133), Afework Edmealem (11237447), Hailie Amha (22560136)   +6 more
openalex   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Risk modeling for esophageal cancer based on adaptive Lasso and Cox regression. [PDF]

Front Oncol
Li X, Han G, Yang Y, Liang E.
europepmc   +1 more source

Cox proportional hazard regression analysis for local recurrence.

Hiroaki Nomori (190889), Cong Yue (3128778), Hiroyoshi Iguchi (22394337), Kenichi Kashihara (707589), Ryuichi Wada (10284647), Tsutomu Saito (5624897)   +5 more
openalex   +1 more source