Semiparametric inference for partially linear regressions with Box-Cox\n transformation [PDF]
, 2021 Daniel Becker +2 more
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Parametrization and penalties in spline models with an application to survival analysis [PDF]
, 2008 In this paper we show how a simple parametrization, built from the definition of cubic splines, can aid in the implementation and interpretation of penalized spline models, whatever configuration of knots we choose to use.
Costa, Maria J. (Maria João) +1 more
core +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Duration Models in Loan Management
Folia Oeconomica Stetinensia, 2015 The purpose of this study is to estimate the future duration of a loan contract on the basis of several factors. The main methodology consists of a brief explanation of a survival analysis and a thorough application of a survival analysis in loan ...
Vasilev Julian A.
doaj +1 more source
Factors associated with extended remission in neovascular age-related macular degeneration on pro re nata treatment protocol. [PDF]
, 2020 AimTo show the characteristics and outcomes of patients with neovascular age-related macular degeneration (nAMD) who had extended remission (ER) while on a pro re nata (PRN) treatment protocol.MethodsThis was a retrospective case-control study of a ...
Amador-Patarroyo, Manuel J +6 more
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High expression of micro RNA-135A in hepatocellular carcinoma is associated with recurrence within 12 months after resection [PDF]
, 2017 Cox Regression analysis subgroup T1 or T2. Table S2. Sequences of target miRNAs used in qPCR analysis. Figure S1. Kaplan-Meier curve subgroup analysis T1 and T2 tumors.
Ansgar W. Lohse +7 more
core +2 more sources
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Molecular Insights and Prognosis Associated With RBM8A in Glioblastoma
Frontiers in Molecular Biosciences, 2022 Background: Glioblastoma (GBM) is the most invasive brain tumors, and it is associated with high rates of recurrence and mortality. The purpose of this study was to investigate the expression of RBM8A in GBM and the potential influence of its expression ...
Lei Wei +7 more
doaj +1 more source
Determinants of healthcare utilisation and predictors of outcome in colorectal cancer patients from Northern Iran [PDF]
, 2016 We aimed to assess healthcare utilisation (HU), its determinants, as well as its relationship with survival in colorectal cancer (CRC) patients. This study was conducted on incident CRC cases from Northern Iran.
Aryaie, M. +8 more
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