Results 141 to 150 of about 31,173 (246)

New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina

open access: yesPathogens, 2019
Coxiella burnetii, the zoonotic agent of Q fever, has a worldwide distribution. Despite the vast information about the circulating genotypes in Europe and North America, there is a lack of data regarding C. burnetii strains in South America.
M. S. Mioni   +7 more
semanticscholar   +1 more source

Horizontally Acquired Biosynthesis Genes Boost Coxiella burnetii's Physiology

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Coxiella burnetii, the etiologic agent of acute Q fever and chronic endocarditis, has a unique biphasic life cycle, which includes a metabolically active intracellular form that occupies a large lysosome-derived acidic vacuole. C.
Abraham S. Moses   +4 more
doaj   +1 more source

High prevalence and two dominant host-specific genotypes of Coxiella burnetii in U.S. milk [PDF]

open access: yes, 2014
BackgroundCoxiella burnetii causes Q fever in humans and Coxiellosis in animals; symptoms range from general malaise to fever, pneumonia, endocarditis and death. Livestock are a significant source of human infection as they shed C.
Birdsell, Dawn M.   +19 more
core   +2 more sources

Host cell depletion of tryptophan by IFNγ-induced Indoleamine 2,3-dioxygenase 1 (IDO1) inhibits lysosomal replication of Coxiella burnetii

open access: yesPLoS Pathogens, 2019
Most intracellular pathogens that reside in a vacuole prevent transit of their compartment to lysosomal organelles. Effector mechanisms induced by the pro-inflammatory cytokine Interferon-gamma (IFNγ) can promote the delivery of pathogen-occupied ...
Sandhya Ganesan, C. Roy
semanticscholar   +1 more source

Serological evidence of Coxiella burnetii infection in cattle and farm workers: is Q fever an underreported zoonotic disease in Ecuador?

open access: yesInfection and Drug Resistance, 2019
Background: Q fever is an underreported zoonotic disease of cattle and men in most countries of the world. Very little information about the prevalence of Coxiella burnetii infection in animals and humans comes from South and Central America and ...
G. Echeverría   +7 more
semanticscholar   +1 more source

Diagnosis and Genotyping of Coxiella burnetii Endocarditis in a Patient with Prosthetic Pulmonary Valve Replacement Using Next-Generation Sequencing of Plasma Microbial Cell-Free DNA

open access: yesOpen Forum Infectious Diseases, 2019
Determining the causative etiology of culture-negative endocarditis can be challenging. We performed next-generation sequencing of plasma microbial cell-free DNA to facilitate rapid diagnosis and genotyping of Coxiella burnetii in a patient with culture ...
Maiko Kondo   +6 more
semanticscholar   +1 more source

Evaluation of the efficiency of detection of bacterial DNA in milk and tissue samples from cattle, sheep, and goats by conventional and nested PCR targeting Com1, sod and Transposase IS1111 genes of Coxiella burnetii genome

open access: yesMacedonian Veterinary Review
Q fever is a worldwide zoonosis, caused by Coxiella burnetii, an obligate intracellular bacterium that affects both humans and animals. The serious consequences on human health and the economic losses it causes, require the use of rapid, accurate, and ...
Konstantin Borisov Simeonov   +2 more
doaj   +1 more source

Phagocytosis of apoptotic cells increases the susceptibility of macrophages to infection with Coxiella burnetii phase II through down-modulation of nitric oxide production [PDF]

open access: yes, 2004
Coxiella burnetii, the agent of Q fever in humans and coxiellosis in other mammals, is an obligate intracellular bacterium which is sheltered and multiplies within typically large phagolysosome-like replicative vacuoles (LRVs).
Rabinovitch, Michel   +1 more
core   +3 more sources

Full-Term Human Placental Macrophages Eliminate Coxiella burnetii Through an IFN-γ Autocrine Loop

open access: yesFrontiers in Microbiology, 2019
The intracellular bacterium Coxiella burnetii is responsible for Q fever, an infectious disease that increases the risk of abortion, preterm labor, and stillbirth in pregnant women. It has been shown that C.
S. Mezouar   +9 more
semanticscholar   +1 more source

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