Modern Approaches to Enterovirus-Based Oncolytic Immune Virotherapy of Malignant Diseases
The aim. The review presents the analysis of publications on modern approaches to oncolytic viral immunotherapy of malignant diseases which is predominantly based on usage of enteroviruses.Materials and methods.
E. R. Nemtsova, E. A. Plotnikova
doaj +1 more source
Enteroviruses and T1D: Is It the Virus, the Genes or Both which Cause T1D
Type 1 diabetes (T1D) is a chronic autoimmune disorder that results from the selective destruction of insulin-producing β-cells in the pancreas. Up to now, the mechanisms triggering the initiation and progression of the disease are, in their complexity ...
Shirin Geravandi +2 more
doaj +1 more source
Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells [PDF]
Coxsackievirus B (CVB), a member of the enterovirus family, targets the polarized epithelial cells lining the intestinal tract early in infection. Although the polarized epithelium functions as a protective barrier, this barrier is likely exploited by ...
Bergelson, JM +6 more
core +1 more source
This study critically analyzed the main advances in ZnO nanomaterials obtained from different synthetic approaches (mediated by plants, microbes and seaweeds), and their functional and biological properties were prospected for applications in the food and nanomedicine sector.
Italo Rennan Sousa Vieira +2 more
wiley +1 more source
Epidemics of enterovirus infection in Chungnam Korea, 2008 and 2009
Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009.
Hwang SeoYeon +11 more
doaj +1 more source
Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells
Enteroviruses manipulate host membranes to form replication organelles, which concentrate viral and host factors to allow for efficient replication. However, this process has not been well-studied in living cells throughout the course of infection.
Nicholas J. Lennemann +2 more
doaj +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis
Studies on inflammatory disorders elucidated the pivotal role of the CX3CL1/CX3CR1 axis with respect to the pathophysiology and diseases progression. Coxsackievirus B3 (CVB3)-induced myocarditis is associated with severe cardiac inflammation, which may ...
I. Müller +12 more
semanticscholar +1 more source
Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization
We present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Allianna Mitchell +7 more
wiley +1 more source
Heparan Sulfates and Coxsackievirus-Adenovirus Receptor: Each One Mediates Coxsackievirus B3 PD Infection [PDF]
ABSTRACT Amino acid exchanges in the virus capsid protein VP1 allow the coxsackievirus B3 variant PD (CVB3 PD) to replicate in decay accelerating factor (DAF)-negative and coxsackievirus-adenovirus receptor (CAR)-negative cells. This suggests that molecules other than DAF and CAR are involved in attachment of this CVB3 variant to
A E, Zautner +4 more
openaire +2 more sources

