Results 111 to 120 of about 22,089 (224)

Cardiac Deletion of the Coxsackievirus-Adenovirus Receptor Abolishes Coxsackievirus B3 Infection and Prevents Myocarditis In Vivo

, 2009
ObjectivesWe investigated the role of the Coxsackievirus-adenovirus receptor (CAR) in viral myocarditis.BackgroundCAR is involved in virus uptake into various cell types.
Gotthardt, Michael, Sauter, M., Lisewski, Ulrike, Shi, Y., Poller, W., Lisewski, U., Uta Wrackmeyer, Michael Gotthardt, Westermann, D., Michael Radke, Ulrike Lisewski, Westermann, Dirk, Klingel, K., Sauter, Martina, Gotthardt, M., Chen, Chen, Tschöpe, Carsten, Karin Klingel, Poller, Wolfgang, Martina Sauter, Chen, C., Radke, M., Dirk Westermann, Wrackmeyer, U., Klingel, Karin, Yu Shi, Chen Chen, Carsten Tschöpe, Radke, Michael, Tschoepe, C., Wolfgang Poller, Shi, Yu, Wrackmeyer, Uta   +32 more
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Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor. [PDF]

, 2014
Contains fulltext : 139327.pdf (Publisher’s version ) (Open Access)The coxsackievirus and adenovirus receptor (CAR) is a cell contact protein with an important role in virus uptake.
Sauter, M., Pinkert, S., Govindarajan, T., Gotthardt, M., Freiberg, F., Fechner, H., Kaldrack, J., Thakkar, M., Klingel, K.   +8 more
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Solution structure of the coxsackievirus and adenovirus receptor domain 1

, 2004
The coxsackievirus and adenovirus receptor (CAR) mediates entry of coxsackievirus B (CVB) and adenovirus (Ad). The normal cellular function of CAR, which is expressed in a wide variety of tissue types, is thought to involve homophilic cell adhesion in ...
Jacobs, Amy, Caffrey, Michael, Laue, Thomas M., Jiang, Shaokai   +3 more
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Coxsackievirus-induced myocarditis : identifying disease mediators

, 2011
Myocarditis-induced dilated cardiomyopathy is a major cause of heart disease and sudden death in young adults. Development of myocarditis is thought to involve both genetic and environmental factors such as pathogen infection, with the most commonly ...
Poffenberger, Maya Chikako
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Coxsackievirus A21 Synergizes with Checkpoint Inhibitors

, 2017
Treatment with a combination of a proprietary formulation of coxsackievirus and either an anti–CTLA-4 or anti–PD-1 checkpoint inhibitor yielded a higher response rate in phase I testing for melanoma than any of these drugs given on their own. Because the

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Rapid diagnosis of acute hemorrhagic conjunctivitis due to coxsackievirus A24 variant by real-time one-step RT-PCR

, 2007
International audienceCoxsackievirus A24 variant is, together with enterovirus 70 and adenoviruses, the major etiological agent involved in acute hemorrhagic conjunctivitis outbreaks worldwide.
Rivat, Nathalie, Norder, Helene, Lina, Bruno, Muyembe, Jean-Jacques, Chomel, Jean-Jacques, Falcon, Delphine, Lahlou Amine, Idriss, Tcheng, Remy, Dussart, Philippe, Eugene, Maxime, Lévêque, Nicolas   +10 more
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Use of Molecular Assay in Diagnosis of Hand, Foot and Mouth Disease Caused by Enterovirus 71 or Coxsackievirus a 16

, 2008
Hand, foot and mouth disease is a common illness in children and is usually caused by coxsackievirus A 16 and enterovirus 71. It has been noted that enterovirus 71 infection is more severe with significantly greater frequency of serious complications and
CHANG, LUAN-YIN, 張鑾英
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Coxsackievirus B4 Uses Autophagy for Replication after Calpain Activation in Rat Primary Neurons

, 2008
Coxsackievirus is the most important cause of meningitis and encephalitis in infants; an infection is sometimes fatal or may lead to neurodevelopmental defects.
Lee, Heuiran, Yoon, Seung Yong, Ahn, Jeonghyun, Kweon, Hee-Seok, Lee, Jee-Young, Choi, Jung Eun, Ha, Young Eun, Kim, Dong Hou   +7 more
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In Vivo and In Vitro Studies Assessing the Antiviral Efficacy of Double Combinations Against Coxsackievirus B Infection

Microorganisms
Coxsackievirus B (CVB) infections, ranging from mild to severe diseases, lack specific antiviral treatments, underscoring the need for novel therapeutic strategies.
Adelina Stoyanova, Simeon Galabov, Vadim Makarov, Angel S. Galabov   +3 more
doaj   +1 more source

Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease

, 2015
Coxsackievirus B3 is the main cause of human viral myocarditis and cardiomyopathy. Virally encoded Coxsackievirus 3C protease (3Cpro) plays an essential role in viral proliferation.
Cho, Joong-Heui, Jeong, Pyeonghwa, Lee, Youngjin, Park, Kyoung Ryoung, Eom, Soo Hyun, Lim, Jia Jia, Kim, Yong-Chul, Kim, Bo-Kyoung   +7 more
core   +1 more source