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Factors associated with knowledge, attitudes, and behaviors regarding antiviral medications for COVID-19 among US adults. [PDF]

open access: yesPLoS ONE
BackgroundLittle is known about public perceptions of antivirals for the treatment of mild-to-moderate COVID-19 in the United States (US). Our objective was to explore adult perceptions toward COVID-19 antivirals to improve outreach communications about ...
E Ivy Oyegun   +7 more
doaj   +2 more sources

Clinical development of antivirals against SARS-CoV-2 and its variants

open access: yesCurrent Research in Microbial Sciences
The unceasing global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) calls for the development of novel therapeutics. Although many newly developed antivirals and repurposed antivirals have been applied to the treatment of ...
Qiaoshuai Lan, Shuai Xia, Jiang Shibo
exaly   +3 more sources

Host-directed therapy with 2-deoxy-D-glucose inhibits human rhinoviruses, endemic coronaviruses, and SARS-CoV-2

open access: yesJournal of Virus Eradication, 2022
Rhinoviruses (RVs) and coronaviruses (CoVs) upregulate host cell metabolic pathways such as glycolysis to meet their bioenergetic demands for rapid multiplication.
Laxmikant Wali   +12 more
doaj   +1 more source

Pneumococcal Serotype Evolution and Burden in European Adults in the Last Decade: A Systematic Review

open access: yesMicroorganisms, 2023
Pneumococcal disease is a major cause of morbidity/mortality worldwide, and vaccination is an important measure in its prevention. Despite European children being vaccinated with pneumococcal conjugate vaccines (PCVs), pneumococcal infections are still a
Rita Teixeira   +3 more
doaj   +1 more source

Estimated Incidence of Symptomatic Lyme Borreliosis Cases in Lublin, Poland in 2021

open access: yesMicroorganisms, 2023
Lyme borreliosis (LB), the most common tick-borne disease in Europe, is endemic to Poland. Despite public health surveillance with mandatory reporting of LB cases by physicians and laboratories, many symptomatic LB cases are not included in surveillance ...
Emily Colby   +11 more
doaj   +1 more source

First evidence of tick-borne encephalitis (TBE) outside of Hokkaido Island in Japan

open access: yesEmerging Microbes and Infections, 2023
Tick-borne encephalitis (TBE) is an infection of the central nervous system caused by the tick-borne encephalitis virus (TBEV). TBE is endemic in parts of Europe and Asia. TBEV is transmitted to humans primarily by Ixodes ticks.
Masayuki Ohira   +29 more
doaj   +1 more source

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

open access: yesMolecules, 2023
Human immunodeficiency virus type I (HIV-1) is a retrovirus that infects cells of the host’s immune system leading to acquired immunodeficiency syndrome and potentially death.
Mahta Mansouri   +17 more
doaj   +1 more source

Strategy, Progress, and Challenges of Drug Repurposing for Efficient Antiviral Discovery

open access: yesFrontiers in Pharmacology, 2021
Emerging or re-emerging viruses are still major threats to public health. Prophylactic vaccines represent the most effective way to prevent virus infection; however, antivirals are more promising for those viruses against which vaccines are not effective
Xinlei Li, Tao Peng
doaj   +1 more source

Meningococcal Disease in the Post–COVID-19 Era: A Time to Prepare

open access: yesInfectious Diseases and Therapy, 2023
The global invasive meningococcal disease (IMD) landscape changed considerably during the COVID-19 pandemic, as evidenced by decreased incidence rates due to COVID-19 mitigation measures, such as limited social contact, physical distancing, mask wearing,
David E. Bloom   +9 more
doaj   +1 more source

Photosensitizing Antivirals

open access: yesMolecules, 2021
Antiviral action of various photosensitizers is already summarized in several comprehensive reviews, and various mechanisms have been proposed for it. However, a critical consideration of the matter of the area is complicated, since the exact mechanisms ...
Kseniya A. Mariewskaya   +5 more
doaj   +1 more source

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