Results 31 to 40 of about 81,316 (266)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Different environmental factors predict the occurrence of tick-borne encephalitis virus (TBEV) and reveal new potential risk areas across Europe via geospatial models

open access: yesInternational Journal of Health Geographics
Background Tick-borne encephalitis (TBE) is the most serious tick-borne viral disease in Europe. Identifying TBE risk areas can be difficult due to hyper focal circulation of the TBE virus (TBEV) between mammals and ticks.
Patrick H. Kelly   +7 more
doaj   +1 more source

Targeting the Host Mitochondria as a Novel Human Cytomegalovirus Antiviral Strategy

open access: yes, 2023
Human cytomegalovirus (HCMV) exploits host mitochondrial function to promote viral replication. HCMV gene products have been described to directly interact and alter functional or structural aspects of host mitochondria.
Kevin J. Zwezdaryk, Lauryn O. Bachman
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Incidence of symptomatic Borrelia burgdorferi sensu lato infection in Romania, 2018−2023

open access: yesParasites & Vectors
Background Lyme borreliosis (LB), caused by Borrelia burgdorferi sensu lato (Bbsl), is the most common tick-borne disease in Europe. Although public health surveillance for LB has been conducted in Romania since 2007, the extent of under-detection of ...
Frederick J. Angulo   +12 more
doaj   +1 more source

Incidence of symptomatic Lyme borreliosis in nine European countries

open access: yesInternational Journal of Infectious Diseases
Objectives: To better understand the Lyme borreliosis (LB) burden in Europe, we aimed to estimate the incidence of symptomatic Borrelia burgdorferi sensu lato (Bbsl) infections after adjusting public health LB surveillance data for under-detection of ...
Frederick J. Angulo   +15 more
doaj   +1 more source

Evaluation of Antibacterial and Antiviral Drug Effectiveness in COVID-19 Therapy: A Data-Driven Retrospective Approach

open access: yesPathophysiology, 2022
The clinical manifestations associated with COVID-19 disease is mainly due to a dysregulated host response related to the overexpression of inflammatory markers.
Rika Yulia   +9 more
doaj   +1 more source

Properties of HCV direct-acting antivirals.

open access: yes, 2015
Properties of HCV direct-acting antivirals.
Susanna Naggie (304827)   +1 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Antiviral Activity of Jamaican Medicinal Plants and Isolated Bioactive Compounds

open access: yesMolecules, 2021
Plants have had historical significance in medicine since the beginning of civilization. The oldest medical pharmacopeias of the African, Arabian, and Asian countries solely utilize plants and herbs to treat pain, oral diseases, skin diseases, microbial ...
Henry Lowe   +5 more
doaj   +1 more source

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