Results 21 to 30 of about 81,316 (266)

Near-Infrared Dyes: Towards Broad-Spectrum Antivirals

open access: yes, 2022
Broad antiviral activity in vitro is known for many organic photosensitizers generating reactive oxygen species under irradiation with visible light. Low tissue penetration of visible light prevents further development of antiviral therapeutics based on ...
Maxim S. Krasilnikov   +4 more
core   +1 more source

Structure-based design of antivirals against Envelope Glycoprotein of dengue virus [PDF]

open access: yes, 2020
Dengue virus (DENV) presents a significant threat to global public health with more than 500,000 hospitalizations and 25,000 deaths annually. Currently, there is no clinically approved antiviral drug to treat DENV infection. The envelope (E) glycoprotein
Anasir, M. I. *   +5 more
core   +1 more source

Nebulized 2-deoxylated glucose analogues inhibit respiratory viral infection in advanced in vitro airway models

open access: yesScientific Reports
Respiratory viral infections, such as those caused by rhinoviruses (RVs) and human corona viruses (HCoV), result in a serious strain on healthcare systems and public health, underscoring an urgent need for inhaled broad-spectrum antiviral therapies ...
Sarah K. Wideman   +11 more
doaj   +1 more source

Publicly available surveillance data on tick-borne encephalitis in Europe, 2023

open access: yesTicks and Tick-Borne Diseases
The European Centre for Disease Prevention and Control (ECDC) defines a case of tick-borne encephalitis (TBE) as an infection by the TBE virus (TBEV) with clinical manifestations of central nervous system inflammation (e.g., meningitis, encephalitis). To
Frederick J․ Angulo   +6 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Epidemiology of invasive meningococcal disease in the United States: review of recent data and identified risk factors

open access: yesFrontiers in Public Health
IntroductionTracking the spread of invasive meningococcal disease (IMD) in the United States is important for identifying risk factors and devising public health strategies to prevent infection.MethodsThe epidemiology of IMD in the United States before ...
Jessica Presa   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Clinical manifestations and outcomes of Tick-borne encephalitis: A systematic literature review

open access: yesTicks and Tick-Borne Diseases
Tick-borne encephalitis (TBE) is caused by a viral infection and can lead to acute and persistent damage to the central and peripheral nervous systems.
Kate Halsby   +9 more
doaj   +1 more source

Transfer of antivirals across the human placenta

open access: yes, 2005
Background: Viruses cross the placenta and infect the fetus. Antivirals are administered to pregnant women to protect them and the fetus against the viruses.
PACIFICI, GIAN MARIA
core   +1 more source

Extracellular Polymeric Substances: Still Promising Antivirals [PDF]

open access: yes, 2022
Sulfated polysaccharides and other polyanions have been promising candidates in antiviral research for decades. These substances gained attention as antivirals when they demonstrated a high inhibitory effect in vitro against human immunodeficiency virus (
Ruiz-Carpio, Vicente   +14 more
core   +1 more source

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