Results 21 to 30 of about 76,225 (259)

Anti-Dengue: A Machine Learning-Assisted Prediction of Small Molecule Antivirals against Dengue Virus and Implications in Drug Repurposing

, 2023
Dengue outbreaks persist in global tropical regions, lacking approved antivirals, necessitating critical therapeutic development against the virus.
Manoj Kumar, Akanksha Rajput, Sakshi Gautam, Anamika Thakur   +3 more
core   +1 more source

Antivirals and Vaccines

, 2023
New antivirals are urgently needed to treat respiratory diseases caused by RNA viruses [...
Nuno Taveira, Taveira, Nuno
core   +1 more source

Direct-acting antivirals for flaviviruses.

, 2022
Direct-acting antivirals for flaviviruses.
Vinod RMT Balasubramaniam (12475307), Thamil Vaani Komarasamy (12475301), Nur Amelia Azreen Adnan (12475304), William James (208100)   +3 more
core   +1 more source

Host-targeting antivirals for flaviviruses.

, 2022
Host-targeting antivirals for flaviviruses.
Vinod RMT Balasubramaniam (12475307), Thamil Vaani Komarasamy (12475301), Nur Amelia Azreen Adnan (12475304), William James (208100)   +3 more
core   +1 more source

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]

, 2012
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda, Dimmock Nigel J., Dove, Brian K., Scott, P. D. (Paul D.), Carroll, Miles W., Linda Cheung, Miles W Carroll, Brian K Dove, Dove Brian K., Taylor Irene, Bassam Hallis, Meng, Bo, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Miles W. Carroll (111071), Dimmock, N. J., Linda Cheung (71020), Andrew J. Easton (111072), Irene Taylor (111066), Scott Paul D., Bo Meng (111065), Hallis Bassam, Taylor, Irene, Andrew J Easton, Paul D Scott, Bo Meng, Brian K. Dove (111063), Meng Bo, Paul D. Scott (111064), Nigel J Dimmock, Marriott Anthony C., Irene Taylor, Anthony C Marriott, Nigel J. Dimmock (111061), Carroll Miles W., Cheung Linda, Bassam Hallis (111069), Easton Andrew J., Anthony C. Marriott (111070)   +39 more
core   +2 more sources

Targeting the Host Mitochondria as a Novel Human Cytomegalovirus Antiviral Strategy

, 2023
Human cytomegalovirus (HCMV) exploits host mitochondrial function to promote viral replication. HCMV gene products have been described to directly interact and alter functional or structural aspects of host mitochondria.
Kevin J. Zwezdaryk, Lauryn O. Bachman
core   +1 more source

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19) [PDF]

, 2020
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion in treatment options. In this study, we investigated the anti-SARS-CoV-2 activities of
Chu, H, Chan, CCY, Kelvin Kai-Wang To, Cai, JP, Kenn Ka-Heng Chik, Jian-Piao Cai, Yin, F, Chik, KKH, Ronghui Liang, Jessica Oi-Ling Tsang, Hin Chu, Dong-Yan Jin, Ivan Fan-Ngai Hung, Cao, J, Shuofeng Yuan, Tang, K, Ye, ZW, Feifei Yin, Hung, IFN, Chris Chun-Yiu Chan, Jin, DY, Chan, JFW, Liang, R, Yuan, S, Tsang, JOL, Kwok-Yung Yuen, Kaiming Tang, Jianli Cao, Zi-Wei Ye, To, KKW, Yuen, KY, Jasper Fuk-Woo Chan   +31 more
core   +1 more source

Characterization of Streptococcus pneumoniae isolates obtained from the middle ear fluid of US children, 2011–2021

Frontiers in Pediatrics
IntroductionPneumococcal conjugate vaccines (PCVs), including higher valency vaccines such as PCV20, have the potential to reduce pediatric otitis media.
Lindsay R. Grant, Kevin Apodaca, Lalitagauri Deshpande, John H. Kimbrough, Kyla Hayford, Qi Yan, Rodrigo Mendes, Alejandro Cané, Bradford D. Gessner, Adriano Arguedas   +9 more
doaj   +1 more source

Coverage of nMABS and antivirals

, 2022
Coverage of neutralising monoclonal antibodies or antivirals for non-hospitalised patients with COVID ...
William Hulme, Linda Nab
core   +1 more source

Nebulized 2-deoxylated glucose analogues inhibit respiratory viral infection in advanced in vitro airway models

Scientific Reports
Respiratory viral infections, such as those caused by rhinoviruses (RVs) and human corona viruses (HCoV), result in a serious strain on healthcare systems and public health, underscoring an urgent need for inhaled broad-spectrum antiviral therapies ...
Sarah K. Wideman, Laxmikant Wali, Vitalii Kovtunyk, Scharon Chou, Vanessa Gusel, Heta Telimaa, Chama Najmi, Delyana Stoeva, Johannes Stöckl, Guido A. Gualdoni, Anna-Dorothea Gorki, Snezana Radivojev   +11 more
doaj   +1 more source