Results 21 to 30 of about 81,316 (266)
Near-Infrared Dyes: Towards Broad-Spectrum Antivirals
Broad antiviral activity in vitro is known for many organic photosensitizers generating reactive oxygen species under irradiation with visible light. Low tissue penetration of visible light prevents further development of antiviral therapeutics based on ...
Maxim S. Krasilnikov +4 more
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Structure-based design of antivirals against Envelope Glycoprotein of dengue virus [PDF]
Dengue virus (DENV) presents a significant threat to global public health with more than 500,000 hospitalizations and 25,000 deaths annually. Currently, there is no clinically approved antiviral drug to treat DENV infection. The envelope (E) glycoprotein
Anasir, M. I. * +5 more
core +1 more source
Respiratory viral infections, such as those caused by rhinoviruses (RVs) and human corona viruses (HCoV), result in a serious strain on healthcare systems and public health, underscoring an urgent need for inhaled broad-spectrum antiviral therapies ...
Sarah K. Wideman +11 more
doaj +1 more source
Publicly available surveillance data on tick-borne encephalitis in Europe, 2023
The European Centre for Disease Prevention and Control (ECDC) defines a case of tick-borne encephalitis (TBE) as an infection by the TBE virus (TBEV) with clinical manifestations of central nervous system inflammation (e.g., meningitis, encephalitis). To
Frederick J․ Angulo +6 more
doaj +1 more source
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba +29 more
wiley +1 more source
IntroductionTracking the spread of invasive meningococcal disease (IMD) in the United States is important for identifying risk factors and devising public health strategies to prevent infection.MethodsThe epidemiology of IMD in the United States before ...
Jessica Presa +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Clinical manifestations and outcomes of Tick-borne encephalitis: A systematic literature review
Tick-borne encephalitis (TBE) is caused by a viral infection and can lead to acute and persistent damage to the central and peripheral nervous systems.
Kate Halsby +9 more
doaj +1 more source
Transfer of antivirals across the human placenta
Background: Viruses cross the placenta and infect the fetus. Antivirals are administered to pregnant women to protect them and the fetus against the viruses.
PACIFICI, GIAN MARIA
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Extracellular Polymeric Substances: Still Promising Antivirals [PDF]
Sulfated polysaccharides and other polyanions have been promising candidates in antiviral research for decades. These substances gained attention as antivirals when they demonstrated a high inhibitory effect in vitro against human immunodeficiency virus (
Ruiz-Carpio, Vicente +14 more
core +1 more source

