Results 11 to 20 of about 30,146 (255)

Inhibitory Effect of Sirtuin6 on EndMT by Regulating Oxidative Stress and Autophagy in Coxsackievirus B3-Induced Cardiac Endothelial Cells. [PDF]

Immun Inflamm Dis
This study found that Sirtuin 6 can inhibit CVB3‐induced endothelial‐to‐mesenchymal transition. This protective effect involves the regulation of oxidative stress and autophagy, providing new experimental evidence for elucidating the pathological mechanisms of viral myocarditis.
Yang Z, Wang Y, Chen J, Shou X, Zhang D, Zhou Z, Liu Q.   +6 more
europepmc   +2 more sources

Coxsackievirus B3 targets TFEB to disrupt lysosomal function

Autophagy, 2021
Coxsackievirus B3 (CVB3) is a prevalent etiological agent for viral myocarditis and neurological disorders, particularly in infants and young children. Virus-encoded proteinases have emerged as cytopathic factors that contribute to disease pathogenesis ...
Y. Mohamud, Hui Tang, Y. Xue, Huitao Liu, C. Ng, A. Bahreyni, Honglin Luo   +6 more
semanticscholar   +1 more source

A Crucial Role of ACBD3 Required for Coxsackievirus Infection in Animal Model Developed by AAV-Mediated CRISPR Genome Editing Technique

Viruses, 2021
Genetic screens using CRISPR/Cas9 have been exploited to discover host–virus interactions. These screens have identified viral dependencies on host proteins during their life cycle and potential antiviral strategies.
Hye Jin Shin, Keun Bon Ku, Soojin Kim, Heon Seok Kim, Yeon-Soo Kim, Bum-Tae Kim, Seong-Jun Kim, Chonsaeng Kim   +7 more
doaj   +1 more source

Coxsackievirus-induced myocarditis

Anales de Pediatría (English Edition), 2022
Miocarditis aguda; Virus ...
Dolader Codina, Paola, Giralt García, Gemma, Ferrer Menduiña, Maria Queralt, Gran Ipiña, Ferran, Esmel Vilomara, Roger   +4 more
openaire   +3 more sources

Coxsackievirus B3—Its Potential as an Oncolytic Virus

Viruses, 2021
Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise untreatable types of cancer. Despite encouraging developments in recent years, the limited fraction of patients responding to therapy has demonstrated the need to ...
Anja Geisler, A. Hazini, Lisanne Heimann, J. Kurreck, H. Fechner   +4 more
semanticscholar   +1 more source

Synthesis, Antitumor and Antiviral In Vitro Activities of New Benzotriazole-Dicarboxamide Derivatives

Frontiers in Chemistry, 2021
Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba, Sandra Piras, Paola Corona, Federico Riu, Roberta Loddo, Ilenia Delogu, Gabriella Collu, Giuseppina Sanna, Paola Caria, Tinuccia Dettori, Antonio Carta   +10 more
doaj   +1 more source

ASSOCIATION OF ANTI-COXSACKIE VIRUS-B IgG WITH AUTOANTIBODIES RELATED TO TYPE 1 DIABETES MELLITUS

The Iraqi Journal of Medical Sciences, 2022
Background: Coxsackievirus B is a virus may cause type 1 diabetes. There are links between Coxsackievirus B infections and type 1 diabetes. The presence of autoantibodies in pancreatic beta cells has been linked to the development of type 1 ...
Hakeem Gh. Hassan, Arwa M. Al-Shuwaikh, Raid K. Al-Auqili   +2 more
doaj   +1 more source

Coxsackievirus A16 in Southern Vietnam [PDF]

Frontiers in Microbiology, 2021
Background: Hand, Foot and Mouth Disease (HFMD) is a major public health concern in the Asia-Pacific region. Most recent HFMD outbreaks have been caused by enterovirus A71 (EV-A71), coxsackievirus A16 (CVA16), CVA10, and CVA6. There has been no report regarding the epidemiology and genetic diversity of CVA16 in Vietnam.
Le Nguyen Truc Nhu, Le Nguyen Thanh Nhan, Nguyen To Anh, Nguyen Thi Thu Hong, Hoang Minh Tu Van, Hoang Minh Tu Van, Tran Tan Thanh, Vu Thi Ty Hang, Do Duong Kim Han, Nguyen Thi Han Ny, Lam Anh Nguyet, Du Tuan Quy, Phan Tu Qui, Truong Huu Khanh, Nguyen Thanh Hung, Ha Manh Tuan, Nguyen Van Vinh Chau, Guy Thwaites, Guy Thwaites, H. Rogier van Doorn, H. Rogier van Doorn, Le Van Tan   +21 more
openaire   +3 more sources

Current status of healthcare-associated enteroviral (non-polio) infections

Инфекция и иммунитет, 2020
Here we present the data on foreign research publications describing healthcare-associated enteroviral (nonpolio) infections (HAI) sought in the Worldwide Database for Nosocomial Outbreaks (Institut für Hygiene und Umweltmedizin ...
A. V. Alimov, E. P. Igonina, I. V. Feldblyum, V. I. Chalapa, Yu. A. Zakharova   +4 more
doaj   +1 more source

Coxsackievirus and Adenovirus Receptor

Definitions, 2020
Coxsackievirus and adenovirus receptor (365 aa, ~40 kDa) is encoded by the human CXADR gene. This protein is involved in both the formation of the epithelial apical junction complex and viral infection.

semanticscholar   +1 more source