Results 71 to 80 of about 2,546 (158)
Coxsackievirus A16 infection stimulates imbalances of T cells in children
Experimental and Therapeutic Medicine, 2015 Immune reaction plays a crucial role in the regulation of the progression of Coxsackievirus A16 (CA16)-infected hand, foot and mouth disease (HFMD). However, no details of T-cell subset frequency or imbalance during the CA16 infection process have been revealed.
Qingming, Luo, Wanjun, Peng, L I, Chen
openaire +3 more sources
Molecules, 2013 A series of substituted heteroaromatic piperazine and piperidine derivatives were found through virtual screening based on the structure of human enterovirus 71 capsid protein VP1.
Xian Zhang +8 more
doaj +1 more source
Hand, Foot, and Mouth Disease (HFMD): An Overview [PDF]
Clinovate: Advances in Medicine and HealthcareBackground: Hand, Foot, and Mouth Disease (HFMD) is a contagious viral infection of mostly young children. The disease is typically associated with lesions on the hands, feet, and the oral cavity with some cases characterized by lesions on the buttocks ...
Saumya Awasthi
doaj +1 more source
The Fecal Virome of Children with Hand, Foot, and Mouth Disease that Tested PCR Negative for Pathogenic Enteroviruses. [PDF]
PLoS ONE, 2015 Hand, foot, and mouth disease (HFMD) affects infant and young children. A viral metagenomic approach was used to identify the eukaryotic viruses in fecal samples from 29 Thai children with clinical diagnosis of HFMD collected during the 2012 outbreak ...
Piyada Linsuwanon +5 more
doaj +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
MedComm, Volume 7, Issue 2, February 2026.RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
International Journal of Infectious Diseases, 2014 Background: During 2012, Changsha experienced a large outbreak of hand, foot, and mouth disease (HFMD), resulting in 25 438 cases, including 42 severe cases and eight deaths.
Jing-Fang Chen +4 more
doaj +1 more source
Mucosal Immunity: The Key to Combating Enteroviruses and Beyond
Journal of Immunology Research, Volume 2026, Issue 1, 2026.Enteroviruses (EVs) lead to 10–15 million symptomatic infections each year in the United States alone. EVs enter through either the gastrointestinal or respiratory mucosa, depending on the specific virus. Since these mucosal surfaces are the primary entry points for viruses, mucosal immunity serves as a crucial first line of defense.
Nida Kalam +2 more
wiley +1 more source
CellsEnteroviruses (EVs), particularly those within the species Enterovirus A and B, represent a significant global public health burden, especially in infants and young children. While often causing self-limiting hand, foot, and mouth disease (HFMD), certain
Yuwei Liu +4 more
doaj +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to the global swine industry due to its extensive genetic diversity and limited vaccine cross‐protection. Antiviral strategies that target both viral infection and host pathological responses are urgently needed.
Xinrong Wang +9 more
wiley +1 more source
GeoHealth, Volume 9, Issue 11, November 2025.Abstract Previous research has primarily focused on the impact of climatic variables and air pollution on Hand, Foot, and Mouth Disease (HFMD). However, there remains limited understanding of how air pollution levels modify these relationships across different regions and populations.
Xin Liu +6 more
wiley +1 more source