Results 51 to 60 of about 2,546 (158)

Hand, Foot and Mouth Disease Caused by Coxsackievirus A6, Thailand, 2012

Emerging Infectious Diseases, 2013
In Thailand, hand, foot, and mouth disease (HFMD) is usually caused by enterovirus 71 or coxsackievirus A16. To determine the cause of a large outbreak of HFMD in Thailand during June–August 2012, we examined patient specimens.
Jiratchaya Puenpa, Thaweesak Chieochansin, Piyada Linsuwanon, Sumeth Korkong, Siwanat Thongkomplew, Preyaporn Vichaiwattana, Apiradee Theamboonlers, Yong Poovorawan   +7 more
doaj   +1 more source

Epidemiology of Recurrent Hand, Foot and Mouth Disease, China, 2008–2015

Emerging Infectious Diseases, 2018
Using China’s national surveillance data on hand, foot and mouth disease (HFMD) for 2008–2015, we described the epidemiologic and virologic features of recurrent HFMD.
Jiao Huang, Qiaohong Liao, Mong How Ooi, Benjamin J. Cowling, Zhaorui Chang, Peng Wu, Fengfeng Liu, Yu Li, Li Luo, Shuanbao Yu, Hongjie Yu, Sheng Wei   +11 more
doaj   +1 more source

Replication kinetics of coxsackievirus A16 in human rhabdomyosarcoma cells

Virologica Sinica, 2012
Coxsackievirus A16 (CVA16), together with enterovirus type 71 (EV71), is responsible for most cases of hand, foot and mouth disease (HFMD) worldwide. Recent findings suggest that the recombination between CVA16 and EV71, and the co-circulation of these two viruses may have contributed to the increase of HFMD cases in China over the past few years.
Jun, Jin, Mingming, Han, Lin, Xu, Dong, An, Wei, Kong, Chunlai, Jiang   +5 more
openaire   +3 more sources

Optimization and Characterization of Candidate Strain for Coxsackievirus A16 Inactivated Vaccine [PDF]

Viruses, 2015
Coxsackievirus A16 (CA16) and enterovirus 71 (EV71), both of which can cause hand, foot and mouth disease (HFMD), are responsible for large epidemics in Asian and Pacific areas. Although inactivated EV71 vaccines have completed testing in phase III clinical trials in Mainland China, CA16 vaccines are still under development.
Li, Jingliang, Liu, Guanchen, Liu, Xin, Yang, Jiaxin, Chang, Junliang, Zhang, Wenyan, Yu, Xiao-Fang   +6 more
openaire   +3 more sources

Study on the interaction between different pathogens of Hand, foot and mouth disease in five regions of China

Frontiers in Public Health, 2022
ObjectivesThis study aims to explore the interaction of different pathogens in Hand, foot and mouth disease (HFMD) by using a mathematical epidemiological model and the reported data in five regions of China.MethodsA cross-regional dataset of reported ...
Zimei Yang, Jia Rui, Li Qi, Wenjing Ye, Yan Niu, Kaiwei Luo, Bin Deng, Shi Zhang, Shanshan Yu, Chan Liu, Peihua Li, Rui Wang, Hongjie Wei, Hesong Zhang, Lijin Huang, Simiao Zuo, Lexin Zhang, Shurui Zhang, Shiting Yang, Yichao Guo, Qinglong Zhao, Shenggen Wu, Qin Li, Yong Chen, Tianmu Chen   +24 more
doaj   +1 more source

Autophagy triggered by MAVS inhibits Coxsackievirus A16 replication

Acta virologica, 2019
Mitochondrial antiviral signaling protein (MAVS), a crucial adaptor protein localized on mitochondria, plays vital roles in various biological processes. Autophagy and apoptosis are two independent and closely linked cell death pathways. But whether MAVS could induce apoptosis and autophagy in rhabdomyosarcoma cells (RD cells) and what is the ...
Y, Shi, Y, Liu, Y, Zheng, Y, Tang, G, Zhu, W, Qiu, L, Huang, S, Han, J, Yin, B, Peng, X, He, W, Liu   +11 more
openaire   +3 more sources

A cysteine protease inhibitor GC376 displays potent antiviral activity against coxsackievirus infection

Current Research in Microbial Sciences, 2023
Infection with coxsackievirus A10 (CV-A10) can cause hand-foot-mouth disease and is also associated with severe complications, including viral pneumonia, aseptic and viral meningitis.
Yongkang Chen, Xiaohong Li, Min Wang, Yuan Li, Jun Fan, Jingjing Yan, Shuye Zhang, Lu Lu, Peng Zou   +8 more
doaj   +1 more source

Epidemics of enterovirus infection in Chungnam Korea, 2008 and 2009

Virology Journal, 2011
Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009.
Hwang SeoYeon, Kim JaeKyung, Rheem InSoo, Yu JeeSuk, Song JaeHyoung, Lee BaeckHee, Park KwiSung, Yeo SangGu, Baek KyoungAh, Choi YoungJin, Cheon DooSung, Park JoonSoo   +11 more
doaj   +1 more source

Incorrect identification of recent Asian strains of Coxsackievirus A16 as human enterovirus 71: Improved primers for the specific detection of human enterovirus 71 by RT PCR

BMC Infectious Diseases, 2004
Background Human enterovirus 71 has emerged as an important pathogen in the Asia Pacific region and it is important to be able to make a rapid and specific diagnosis for outbreak control. Recent Asian strains of Coxsackievirus A16 have changes in the VP1
Tan Cheng-Siang, Akin Winnie, Podin Yuwana, Perera David, Cardosa Mary   +4 more
doaj   +1 more source

Immune responses of a CV-A16 live attenuated candidate strain and its protective effects in rhesus monkeys

Emerging Microbes and Infections, 2020
Coxsackievirus A16 (CV-A16) is a major causative pathogen of hand, foot, and mouth diseases (HFMDs). The licensed HFMD vaccine targets EV-A71 without cross-protection against CV-A16. Thus, a CV-A16 vaccine is needed. In this study, the immunogenicity and
Ting Yang, Tianhong Xie, Hua Li, Xia Song, Lei Yue, Xi Wang, Dong Shen, Kaili Ma, Qinfang Jiang, Runxiang Long, Rong Yang, Xin He, Ye Zhang, Zhongping Xie, Qihan Li   +14 more
doaj   +1 more source